SCHEMBL20062968

SCHEMBL20062968

c1cncc(Nc2ccccc2Nc2cccnc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.55
RAD52 P43351 1/20 0.55
PKM P14618 2/20 0.50
ADRA2A P08913 2/20 0.50
ADRA2B P18089 2/20 0.50
ADRA2C P18825 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
CFTR P13569 1/20 0.50
GOPC Q9HD26 1/20 0.50
HTT P42858 1/20 0.49
TDP2 O95551 1/20 0.49
NSD2 O96028 1/20 0.49
KDR P35968 1/20 0.49
KIF11 P52732 1/20 0.49
CCNK O75909 1/20 0.48
CCNA2 P20248 1/20 0.48
CDK2 P24941 1/20 0.48
CCND3 P30281 1/20 0.48
CDK9 P50750 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29414656 0.86 MAPT (0.62) KMT2ARAD52PKMADRA2AADRA2B
SCHEMBL11100945 0.86 PKM (0.62) KMT2ARAD52PKMADRA2AADRA2B
SCHEMBL1239861 0.86 MAPT (0.62) KMT2ARAD52PKMADRA2AADRA2B
SCHEMBL9173823 0.86 CCNA2 (0.63) KMT2ARAD52NPC1RAB9AHTT
SCHEMBL29793056 0.85 KIF11 (0.60) KMT2ARAD52PKMADRA2AADRA2B
SCHEMBL1368828 0.85 KIF11 (0.60) KMT2ARAD52PKMADRA2AADRA2B
SCHEMBL4591751 0.84 KMT2A (0.61) KMT2ARAD52PKMADRA2AADRA2B
SCHEMBL29845262 0.84 KMT2A (0.61) KMT2ARAD52PKMADRA2AADRA2B
SCHEMBL17646086 0.83 KDR (0.51) KMT2ARAD52PKMADRA2CNPC1
SCHEMBL15901656 0.83 ALDH1A1 (0.65) KMT2ARAD52ADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 KMT2A 2024/4885RAD52 438/4885PKM 4643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.