SCHEMBL29414657

SCHEMBL29414657

Cc1ccc(-c2cccc(N)c2N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.48
ADORA2A P29274 2/20 0.43
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP3A4 P08684 2/20 0.42
TSHR P16473 1/20 0.42
PIK3CA P42336 1/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PARP1 P09874 1/20 0.40
ACHE P22303 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 3/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
KIT P10721 2/20 0.35
KDR P35968 2/20 0.35
FLT3 P36888 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2602432 1.00 CD44 (0.48) CD44ADORA2AALDH1A1HSD17B10CYP3A4
SCHEMBL28621174 0.90 ALDH1A1 (0.43) CD44ADORA2AALDH1A1HSD17B10CYP3A4
SCHEMBL6318211 0.89 NPC1 (0.44) CD44ADORA2AALDH1A1HSD17B10CYP3A4
SCHEMBL5647993 0.83 CYP3A4 (0.54) CD44ADORA2AALDH1A1HSD17B10CYP3A4
SCHEMBL24528368 0.83 ALDH1A1 (0.48) ADORA2AALDH1A1HSD17B10CYP3A4TSHR
SCHEMBL1263501 0.82 ADORA2A (0.39) CD44ADORA2AALDH1A1HSD17B10CYP3A4
SCHEMBL4749661 0.82 ALDH1A1 (0.46) CD44ALDH1A1HSD17B10CYP3A4TSHR
SCHEMBL394565 0.82 ALDH1A1 (0.65) ADORA2AALDH1A1HSD17B10CYP3A4TSHR
SCHEMBL2944534 0.81 CD44 (0.46) CD44ADORA2AALDH1A1HSD17B10CYP3A4
SCHEMBL23625587 0.81 ALDH1A1 (0.54) ADORA2AALDH1A1HSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111747933-B Substituted 1,3, 5-triazine compound, composition and application thereof 吉林省元合电子材料有限公司 2022-03-01 CN disclosed