Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CD44 | P16070 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24528368 | 0.93 | ALDH1A1 (0.48) | NPC1RAB9AMEN1KMT2AACHE | |
| SCHEMBL29414657 | 0.89 | CD44 (0.48) | NPC1RAB9AMEN1KMT2AACHE | |
| SCHEMBL2602432 | 0.89 | CD44 (0.48) | NPC1RAB9AMEN1KMT2AACHE | |
| SCHEMBL31010762 | 0.85 | NPC1 (0.39) | NPC1RAB9AMEN1KMT2AACHE | |
| SCHEMBL10464566 | 0.85 | NPC1 (0.39) | NPC1RAB9AMEN1KMT2AACHE | |
| SCHEMBL28367275 | 0.84 | ALDH1A1 (0.57) | ADORA2AALDH1A1ADORA1 | |
| SCHEMBL23430418 | 0.84 | MEN1 (0.46) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL13515175 | 0.84 | ACHE (0.48) | NPC1RAB9AMEN1KMT2AACHE | |
| SCHEMBL28621175 | 0.81 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AACHE | |
| SCHEMBL9685314 | 0.80 | ESR2 (0.44) | NPC1RAB9AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916893-B2 | Polymerization-active transition metal complexes having bulky ligand systems | SER. V. GMBH (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040171774-A1 | Polymerization-active transition metal complexes having bulky ligand systems | RIEGER BERNHARD (DE) | 2004-09-02 | — | — | US | disclosed |
| EP-1242434-B1 | POLYMERIZATION-ACTIVE TRANSITION METAL COMPLEX COMPOUNDS COMPRISING A STERICALLY DEMANDING LIGAND SYSTEM | SER V GMBH (DE) | 2004-06-02 | — | — | EP | disclosed |
| EP-1398330-A2 | Transition metal complexes having a bulky ligand system used in polymerisation | Ser.V. GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171774-A1 | Polymerization-active transition metal complexes having bulky ligand systems | AP1M1, CCNC, CLTB | NPC1 2492/4885RAB9A 2215/4885MEN1 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.