Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 4/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414698 | 0.88 | EGFR (0.66) | KDM4EALDH1A1HTTCYP2C19HSD17B10 | |
| SCHEMBL6671401 | 0.88 | EGFR (0.66) | KDM4EALDH1A1HTTCYP2C19HSD17B10 | |
| SCHEMBL10085033 | 0.81 | MAPT (0.47) | KDM4EALDH1A1HTTCYP2C19HSD17B10 | |
| SCHEMBL29372620 | 0.81 | EGFR (0.54) | KDM4EALDH1A1HTTCYP2C19HSD17B10 | |
| SCHEMBL30002016 | 0.77 | AXL (0.52) | KDM4EALDH1A1CYP2C19HSD17B10HPGD | |
| SCHEMBL984736 | 0.76 | EGFR (0.65) | KDM4EALDH1A1HTTCYP2C19HSD17B10 | |
| SCHEMBL7278316 | 0.76 | EGFR (0.65) | KDM4EALDH1A1HTTCYP2C19HSD17B10 | |
| SCHEMBL30443220 | 0.76 | EGFR (0.65) | KDM4EALDH1A1HTTCYP2C19HSD17B10 | |
| SCHEMBL28794033 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1HTTCYP2C19HSD17B10 | |
| SCHEMBL10518625 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1HTTCYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253283-A1 | PROTEIN KINASE DEGRADANT AND USE THEREOF | 中国科学院上海有机化学研究所 | 2022-12-08 | — | — | WO | disclosed |