SCHEMBL28295413

SCHEMBL28295413

Cc1c(C(N)=O)c2ccccc2n1-c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.55
GFER P55789 1/20 0.55
PLA2G2A P14555 1/20 0.55
RORC P51449 1/20 0.54
HPGD P15428 2/20 0.54
HTT P42858 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
LMNA P02545 1/20 0.54
PTK2B Q14289 1/20 0.54
KDM4E B2RXH2 3/20 0.51
MAPT P10636 3/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
PKM P14618 1/20 0.51
ALOX15 P16050 1/20 0.51
CYP2C19 P33261 1/20 0.51
HSD17B10 Q99714 1/20 0.51
EGFR P00533 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15175928 0.87 GAA (0.70) GAAGFERPLA2G2ARORCHPGD
SCHEMBL6671401 0.81 EGFR (0.66) GAAHPGDHTTLMNAKDM4E
SCHEMBL29414698 0.81 EGFR (0.66) GAAHPGDHTTLMNAKDM4E
SCHEMBL16344509 0.81 MAPT (0.75) GAAGFERPLA2G2ARORCHPGD
SCHEMBL25919164 0.81 USP14 (0.55) GAAGFERPLA2G2ARORCHPGD
SCHEMBL579199 0.81 KDM4E (0.48) GAAGFERPLA2G2ARORCPTK2B
SCHEMBL25712302 0.80 USP14 (0.57) GAAGFERPLA2G2ARORCHPGD
SCHEMBL28285344 0.79 IL1R1 (0.54) GAAPLA2G2AHPGDHTTSMN1; SMN2
SCHEMBL2885250 0.79 MEN1 (0.74) GAAHPGDSMN1; SMN2KDM4EMAPT
Hydrochloric Acid SCHEMBL28283710 0.78 ALDH1A1 (0.55) GAAPLA2G2AHPGDHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109761875-A A kind of new method constructing amido bond 盐城工学院 2019-05-17 CN disclosed