Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2910330 | 0.99 | RAB9A (0.43) | RAB9ALMNAMAPTHPGDBTK | |
| SCHEMBL2910244 | 0.92 | NPY5R (0.44) | RAB9ALMNAMAPTHPGDKDR | |
| SCHEMBL4360388 | 0.88 | RAB9A (0.50) | RAB9ALMNAMAPTHPGDF13A1 | |
| SCHEMBL2914956 | 0.81 | MAPT (0.43) | RAB9ALMNAMAPTHPGDBTK | |
| SCHEMBL2910241 | 0.80 | ALDH1A1 (0.62) | RAB9ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL2919940 | 0.80 | MAPT (0.44) | RAB9ALMNAMAPTHPGDBTK | |
| Hydrochloric Acid SCHEMBL2910327 | 0.80 | ALDH1A1 (0.61) | RAB9ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL4361554 | 0.77 | SIRT2 (0.49) | RAB9ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL4363710 | 0.77 | NPC1 (0.46) | RAB9ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL2944777 | 0.75 | S1PR1 (0.44) | LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709047-B1 | AZABENZOFURAN SUBSTITUTED THIOUREAS AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS INC (US) | 2010-09-01 | — | — | EP | claimed |