Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.59 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.59 |
| ▸ | GALR3 | O60755 | 2/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1516426 | 1.00 | ALDH1A1 (0.64) | ALDH1A1ITGB1ITGA4GALR3NR2F2 | |
| SCHEMBL30587068 | 1.00 | ALDH1A1 (0.64) | ALDH1A1ITGB1ITGA4GALR3NR2F2 | |
| SCHEMBL31052848 | 0.83 | ITGB1 (0.54) | ALDH1A1ITGB1ITGA4GALR3NR2F2 | |
| SCHEMBL14285630 | 0.82 | ITGB1 (0.53) | ALDH1A1ITGB1ITGA4GALR3NR2F2 | |
| SCHEMBL30250339 | 0.81 | SMN1; SMN2 (0.56) | ALDH1A1ITGB1ITGA4LMNASMN1; SMN2 | |
| SCHEMBL29416388 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1ITGB1ITGA4SMN1; SMN2NPSR1 | |
| SCHEMBL31392415 | 0.81 | ALDH1A1 (0.72) | ALDH1A1LMNASMN1; SMN2ADORA3KMT2A | |
| SCHEMBL31052913 | 0.80 | ITGB1 (0.51) | ALDH1A1ITGB1ITGA4GALR3NR2F2 | |
| SCHEMBL31392369 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2NPSR1PRNPTSHR | |
| SCHEMBL8497711 | 0.79 | ITGB1 (0.60) | ALDH1A1ITGB1ITGA4GALR3NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072206-A1 | INTEGRIN INHIBITORS FOR TREATMENT OF PRIMARY SCLEROSING CHOLANGITIS | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | claimed |
| CN-115989235-A | Methods of treating respiratory diseases using amino acid compounds | 普利安特治疗公司 | 2023-04-18 | — | — | CN | claimed |
| CN-120091811-A | Integrin inhibitors and their use in combination with other agents | 普利安特治疗公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2025072206-A1 | INTEGRIN INHIBITORS FOR TREATMENT OF PRIMARY SCLEROSING CHOLANGITIS | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| EP-4525866-A1 | STABILIZATION OF INTEGRIN INHIBITORS | Pliant Therapeutics, Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| CN-118401521-A | Integrin inhibitors and their use in combination with other agents | 普利安特治疗公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-117615760-A | Extended dosage regimen for integrin inhibitors | 普利安特治疗公司 | 2024-02-27 | — | — | CN | disclosed |
| WO-2023225119-A1 | STABILIZATION OF INTEGRIN INHIBITORS | PLIANT THERAPEUTICS, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| EP-4247472-A1 | INTEGRIN INHIBITOR AND USES THEREOF | Pliant Therapeutics, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116710169-A | Integrin inhibitors and uses thereof | 普利安特治疗公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115989235-A | Methods of treating respiratory diseases using amino acid compounds | 普利安特治疗公司 | 2023-04-18 | — | — | CN | disclosed |
| EP-4146264-A1 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | Pliant Therapeutics, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |
| WO-2022109598-A1 | INTEGRIN INHIBITOR AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |