Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 11/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18810063 | 1.00 | PTGES (0.41) | PTGESARERCC1ERCC4P2RX7 | |
| SCHEMBL18809972 | 0.86 | PTGES (0.43) | PTGES | |
| SCHEMBL18810208 | 0.86 | PTGES (0.44) | PTGESARP2RX7 | |
| SCHEMBL9946581 | 0.82 | RIPK1 (0.42) | PTGESARP2RX7 | |
| SCHEMBL22155229 | 0.74 | CXCR2 (0.35) | — | |
| SCHEMBL18810064 | 0.73 | PTGES (0.40) | PTGESERCC1ERCC4P2RX7SLC1A2 | |
| SCHEMBL18809969 | 0.73 | ERCC1 (0.55) | PTGESARERCC1ERCC4 | |
| SCHEMBL29417087 | 0.73 | ERCC1 (0.55) | PTGESARERCC1ERCC4 | |
| Hydrochloric Acid SCHEMBL29417270 | 0.72 | PTGES (0.39) | PTGESERCC1ERCC4P2RX7SLC1A2 | |
| Hydrochloric Acid SCHEMBL20489865 | 0.72 | PTGES (0.39) | PTGESERCC1ERCC4P2RX7SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137513-B | Pyrimidine derivatives | ASKA 制药株式会社 | 2022-03-01 | — | — | CN | disclosed |