Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.46 |
| ▸ | HTR2A | P28223 | 10/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164579 | 1.00 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2PYCR1HRH3 | |
| SCHEMBL31163135 | 0.83 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2HRH3CHRNB2 | |
| SCHEMBL6911962 | 0.83 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2HRH3CHRNB2 | |
| SCHEMBL28879829 | 0.81 | SLC6A4 (0.47) | SLC6A4HTR2AKCNH2PYCR1HRH3 | |
| SCHEMBL8169154 | 0.80 | CHRNA7 (0.53) | HTR2APYCR1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL24270084 | 0.79 | PYCR1 (0.41) | SLC6A4HTR2AKCNH2PYCR1HRH3 | |
| SCHEMBL1872934 | 0.78 | KDM4E (0.51) | SLC6A4HTR2AKCNH2PYCR1SLC6A2 | |
| SCHEMBL4115232 | 0.78 | SLC6A4 (0.45) | SLC6A4HTR2AKCNH2HRH3CHRNB2 | |
| SCHEMBL18839297 | 0.78 | KDM1A (0.48) | SLC6A4HTR2AKCNH2PYCR1HRH3 | |
| SCHEMBL18107706 | 0.78 | SLC6A4 (0.45) | SLC6A4HTR2AKCNH2HRH3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032019-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2022-02-10 | — | — | WO | disclosed |