SCHEMBL29419084

SCHEMBL29419084

COc1cc(C)c(C(=O)c2c(OC)ncc(Br)c2C)c(OC)c1OC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.37
TSHR P16473 3/20 0.36
APOBEC3A P31941 1/20 0.36
HTT P42858 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
ULK1 O75385 3/20 0.36
PRKAA2 P54646 1/20 0.36
PRKAA1 Q13131 1/20 0.36
ULK2 Q8IYT8 1/20 0.36
KMT2A Q03164 2/20 0.35
POLB P06746 2/20 0.35
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
GFER P55789 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TNFRSF1A P19438 2/20 0.34
ALDH1A1 P00352 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119728 1.00 PTPN1 (0.37) PTPN1TSHRAPOBEC3AHTTAPOBEC3G
SCHEMBL676320 0.90 PTPN1 (0.40) PTPN1TSHRAPOBEC3AHTTAPOBEC3G
SCHEMBL675835 0.88 POLB (0.37) PTPN1HTTKMT2APOLBMEN1
SCHEMBL526805 0.88 PTPN1 (0.36) PTPN1TSHRAPOBEC3AHTTAPOBEC3G
SCHEMBL29358934 0.88 PTPN1 (0.36) PTPN1TSHRAPOBEC3AHTTAPOBEC3G
SCHEMBL676354 0.86 PTPN1 (0.41) PTPN1TSHRAPOBEC3AHTTAPOBEC3G
SCHEMBL322562 0.85 HPGD (0.35) PTPN1ULK1KMT2APOLBMEN1
SCHEMBL29351890 0.85 HPGD (0.35) PTPN1ULK1KMT2APOLBMEN1
SCHEMBL29814930 0.85 HPGD (0.35) PTPN1ULK1KMT2APOLBMEN1
SCHEMBL20302770 0.85 PTPN1 (0.34) PTPN1TSHRAPOBEC3AHTTAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN claimed
CN-120136787-A Pyrazole-substituted aryl sulfide compound and application thereof 青岛清原化合物有限公司 2025-06-13 CN disclosed
US-12245593-B2 Agricultural products and related methods CYTOZYME LABORATORIES, INC. (US) 2025-03-11 US disclosed
CN-118947730-A Plant treatment products and related methods 美国赛多美科技有限公司 2024-11-15 CN disclosed
CN-118955472-A 2- (Hetero) aryl substituted fused heterocyclic derivatives as pesticides 拜耳作物科学股份公司 2024-11-15 CN disclosed
CN-110678076-B Plant treatment products and related methods 美国赛多美科技有限公司 2024-07-23 CN disclosed
CN-118265453-A Protein aggregation inhibiting compounds for plant disease control 马克斯·普朗克科学促进学会 2024-06-28 CN disclosed
EP-4384013-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (DE) 2024-06-19 EP disclosed
CN-110475776-B Tricyclic carboxamides for combating arthropods 拜耳作物科学股份公司 2024-03-19 CN disclosed
EP-4298908-A2 TRICYCLIC CARBOXAMIDES FOR THE CONTROL OF ARTHROPODS Bayer Animal Health GmbH (DE) 2024-01-03 EP disclosed
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN disclosed
US-11632958-B2 Use of fungicides for controlling mosaic scab in apples BAYER AKTIENGESELLSCHAFT (DE) 2023-04-25 US disclosed
EP-3556211-B1 ORGANIC AMMONIUM SALTS OF ANIONIC PESTICIDES CLARIANT INT LTD (CH) 2023-01-25 EP disclosed
EP-4061798-A1 SOLVATES OF ABSCISIC ACID AND LIQUID COMPOSITIONS CONTAINING ABSCISIC ACID Clariant International Ltd (CH) 2022-09-28 EP disclosed
WO-2022128955-A1 STORAGE STABLE AQUEOUS SUSPENSION CONCENTRATES BAYER AKTIENGESELLSCHAFT (DE) 2022-06-23 WO disclosed
CN-114466836-A Solvates of abscisic acid and liquid compositions containing abscisic acid 科莱恩国际有限公司 2022-05-10 CN disclosed
CN-109561676-B Use of N-substituted pyrrolidones for promoting penetration of agrochemical active ingredients 科莱恩国际有限公司 2022-04-29 CN disclosed
CN-113243374-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2022-04-26 CN disclosed
CN-109310082-B Timed release granular agrochemical composition and process for producing the same 拜耳农作物科学股份公司 2022-03-29 CN disclosed
CN-114158553-A Novel pesticide preparation and preparation method thereof 南开沧州渤海新区绿色化工研究有限公司 2022-03-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11632958-B2 Use of fungicides for controlling mosaic scab in apples SACM1L, PPM1B, PSPH PTPN1 666/4885TSHR 4451/4885APOBEC3A 1232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.