SCHEMBL526805

SCHEMBL526805

COc1cc(C)c(C(=O)c2c(OC)ncc(Br)c2Cl)c(OC)c1OC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.36
ULK1 O75385 3/20 0.35
PRKAA2 P54646 1/20 0.35
PRKAA1 Q13131 1/20 0.35
ULK2 Q8IYT8 1/20 0.35
HTT P42858 2/20 0.35
TSHR P16473 2/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
POLB P06746 2/20 0.33
TNFRSF1A P19438 2/20 0.33
MAPT P10636 3/20 0.32
LMNA P02545 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
HPGD P15428 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NCOA1 Q15788 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358934 1.00 PTPN1 (0.36) PTPN1ULK1PRKAA2PRKAA1ULK2
SCHEMBL676115 0.91 TNFRSF1A (0.37) PTPN1ULK1PRKAA2PRKAA1ULK2
SCHEMBL676192 0.89 LMNA (0.34) PTPN1POLBMAPTLMNAHPGD
SCHEMBL676223 0.88 ALDH1A1 (0.35) ULK1POLBMAPTLMNAHPGD
SCHEMBL29419084 0.88 PTPN1 (0.37) PTPN1ULK1PRKAA2PRKAA1ULK2
SCHEMBL119728 0.88 PTPN1 (0.37) PTPN1ULK1PRKAA2PRKAA1ULK2
SCHEMBL676320 0.88 PTPN1 (0.40) PTPN1ULK1PRKAA2PRKAA1ULK2
SCHEMBL675072 0.86 PTPN1 (0.39) PTPN1ULK1HTTTSHRAPOBEC3A
SCHEMBL674838 0.86 TUBB4A (0.32) PTPN1POLBMAPTLMNAHPGD
SCHEMBL674954 0.85 ALDH1A1 (0.36) PTPN1ULK1POLBMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115606598-A Fungicidal composition and method for controlling harmful fungi 石原产业株式会社 2023-01-17 CN claimed
CN-113598173-A Fungicidal composition and method for controlling harmful fungi 石原产业株式会社 2021-11-05 CN claimed
US-10136643-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2018-11-27 US claimed
EP-2205096-B1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING NOXIOUS FUNGI ISHIHARA SANGYO KAISHA (JP) 2017-04-12 EP claimed
US-20160353737-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2016-12-08 US claimed
US-9474281-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2016-10-25 US claimed
US-20150164084-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2015-06-18 US claimed
EP-1679003-B1 BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA (JP) 2015-04-15 EP claimed
US-8962661-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2015-02-24 US claimed
US-8568755-B2 Fungicidal composition and method for controlling noxious fungi ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-10-29 US claimed
US-20100255116-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING NOXIOUS FUNGI ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-10-07 US claimed
CN-101822253-A The method of control of microbicide compositions and plant disease ISHIHARA SANGYO KAISHA 2010-09-08 CN claimed
CN-100581362-C Bactericide composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA 2010-01-20 CN claimed
WO-2010002026-A2 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-01-07 WO claimed
EP-2036436-A1 ANTIBACTERIAL COMPOSITION AND METHOD FOR CONTROL OF PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-03-18 EP claimed
CN-101199274-A Bactericide composition and method for controlling plant disease ISHIHARA SANGYO KAISHA (JP) 2008-06-18 CN claimed
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-08-31 US claimed
EP-1679003-A1 BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-07-12 EP claimed
US-20060089390-A1 3-benzoyl-2,4,5-substituted pyridine derivatives or salts thereof and bactericides containing the same ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-04-27 US claimed
EP-1559320-A1 3-BENZOYL-2,4,5-SUBSTITUTED PYRIDINE DERIVATIVES OR SALTS THEREOF AND BACTERICIDES CONTAINING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 2005-08-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160353737-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES AFF4, HCN4, CNPY2 PTPN1 357/4885ULK1 4589/4885PRKAA2 3801/4885
US-20150164084-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES AFF4, HCN4, CNPY2 PTPN1 357/4885ULK1 4589/4885PRKAA2 3801/4885
US-10136643-B2 Fungicidal composition and method for controlling plant diseases AFF4, HCN4, CNPY2 PTPN1 357/4885ULK1 4589/4885PRKAA2 3801/4885
US-20100255116-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING NOXIOUS FUNGI DPM1, ETF1, GABBR1 PTPN1 299/4885ULK1 1695/4885PRKAA2 3795/4885
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases CBR3, CNPY2, PAH PTPN1 427/4885ULK1 4027/4885PRKAA2 1551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.