SCHEMBL676354

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL676320	0.91	PTPN1 (0.40)	PTPN1ALDH1A1TSHRSMN1; SMN2PPARG
	SCHEMBL675072	0.89	PTPN1 (0.39)	PTPN1ALDH1A1TSHRSMN1; SMN2KMT2A
	SCHEMBL675835	0.87	POLB (0.37)	PTPN1ALDH1A1SMN1; SMN2KMT2AHTT
	SCHEMBL119728	0.86	PTPN1 (0.37)	PTPN1ALDH1A1TSHRSMN1; SMN2PPARG
	SCHEMBL29419084	0.86	PTPN1 (0.37)	PTPN1ALDH1A1TSHRSMN1; SMN2PPARG
	SCHEMBL676192	0.85	LMNA (0.34)	PTPN1ALDH1A1SMN1; SMN2KMT2APOLB
	SCHEMBL526805	0.84	PTPN1 (0.36)	PTPN1ALDH1A1TSHRSMN1; SMN2NCOA1
	SCHEMBL29358934	0.84	PTPN1 (0.36)	PTPN1ALDH1A1TSHRSMN1; SMN2NCOA1
	SCHEMBL674954	0.83	ALDH1A1 (0.36)	PTPN1ALDH1A1SMN1; SMN2KMT2APOLB
	SCHEMBL675374	0.82	POLB (0.33)	PTPN1ALDH1A1SMN1; SMN2KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.