Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.65 |
| ▸ | HPGDS | O60760 | 1/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | ATP4A | P20648 | 3/20 | 0.55 |
| ▸ | ATP4B | P51164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24590484 | 1.00 | VCP (0.65) | VCPHPGDSKDM1ACYP19A1PTGS2 | |
| SCHEMBL30294202 | 0.86 | VCP (0.64) | VCPHPGDSKDM1ACYP19A1PTGS2 | |
| SCHEMBL2475685 | 0.86 | VCP (0.64) | VCPHPGDSKDM1ACYP19A1PTGS2 | |
| SCHEMBL24590483 | 0.84 | VCP (0.61) | VCPHPGDSKDM1ACYP19A1PTGS2 | |
| SCHEMBL24590202 | 0.84 | VCP (0.61) | VCPHPGDSKDM1ACYP19A1PTGS2 | |
| SCHEMBL12510242 | 0.82 | VCP (0.60) | VCPHPGDSKDM1ACYP19A1PTGS2 | |
| SCHEMBL2398632 | 0.82 | MAPT (0.48) | VCPHPGDSKDM1ACYP19A1PTGS2 | |
| SCHEMBL10809236 | 0.82 | HPGDS (0.65) | VCPHPGDSKDM1AATP4AATP4B | |
| SCHEMBL1915828 | 0.82 | SCN9A (0.52) | VCPHPGDSKDM1APTGS2ATP4A | |
| SCHEMBL10924221 | 0.82 | HPGDS (0.65) | VCPHPGDSKDM1ACYP19A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849013-B | Cyanopyrrolidines as DUB inhibitors for the treatment of cancer | 特殊治疗有限公司 | 2022-03-29 | — | — | CN | disclosed |