Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115953 | 0.89 | HTR2A (0.54) | CYP3A4MTNR1AMTNR1BTAAR1 | |
| SCHEMBL2399645 | 0.87 | MTNR1A (0.49) | CYP3A4HSP90AB1HSD17B10HMGCRMTNR1A | |
| SCHEMBL4673015 | 0.85 | CYP3A4 (0.51) | CYP3A4HSP90AB1HSD17B10HMGCRMTNR1A | |
| SCHEMBL29025520 | 0.83 | MTNR1A (0.60) | CYP3A4HSP90AB1HMGCRMTNR1AMTNR1B | |
| SCHEMBL9990598 | 0.83 | MTNR1A (0.60) | CYP3A4MTNR1AMTNR1B | |
| SCHEMBL27176767 | 0.82 | MTNR1A (0.46) | CYP3A4MTNR1AMTNR1BALDH1A1TAAR1 | |
| SCHEMBL14354674 | 0.81 | HSP90AB1 (0.56) | HSP90AB1HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL23362766 | 0.81 | SMN1; SMN2 (0.52) | CYP3A4HSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL197773 | 0.81 | HTT (0.53) | CYP3A4HSP90AB1HMGCRMTNR1AMTNR1B | |
| SCHEMBL14394936 | 0.81 | MEN1 (0.47) | CYP3A4HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11285147-B2 | Neuroprotective agents for treatment of neurodegenerative diseases | WAYNE STATE UNIVERSITY (US) | 2022-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11285147-B2 | Neuroprotective agents for treatment of neurodegenerative diseases | PARK7, SMN1; SMN2, CLN6 | CYP3A4 4184/4885HSP90AB1 3402/4885HSD17B10 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.