SCHEMBL29421174

SCHEMBL29421174

CC(C)[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 10/20 0.37
▸ OPRD1 P41143 1/20 0.36
▸ CTSD P07339 3/20 0.35
▸ FNTA P49354 4/20 0.35
▸ FNTB P49356 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30390358 0.93 CD274 (0.41) BACE1OPRD1CTSD
SCHEMBL29421173 0.93 BACE1 (0.38) BACE1OPRD1CTSDFNTAFNTB
SCHEMBL30567410 0.91 BACE1 (0.38) BACE1OPRD1CTSDFNTAFNTB
SCHEMBL30254038 0.91 BACE1 (0.38) BACE1OPRD1CTSDFNTAFNTB
SCHEMBL29630382 0.89 BACE1 (0.36) BACE1CTSD
SCHEMBL30020949 0.89 BACE1 (0.49) BACE1OPRD1CTSD
SCHEMBL31474495 0.89 BACE1 (0.33) BACE1OPRD1
SCHEMBL30873786 0.88 BACE1 (0.48) BACE1CTSD
SCHEMBL29630322 0.88 BACE1 (0.41) BACE1OPRD1CTSD
SCHEMBL29591626 0.88 BACE1 (0.41) BACE1OPRD1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116875567-A Protein-linked zymogen or enzyme from Phyllostachys pubescens and application thereof 安徽同科生物科技有限公司 2023-10-13 — — CN claimed
US-20250179162-A1 ANTIGEN BINDING FRAGMENTS CONJUGATED TO A PLURALITY OF FC ISOTYPES AND SUBCLASSES BIO-RAD ABD SEROTEC GMBH (DE) 2025-06-05 — — US disclosed
CN-113811548-B Antigen binding proteins 生物辐射ABD瑟罗泰克有限公司 2025-04-04 — — CN disclosed
CN-114746121-B Pentapeptides and methods of use thereof 伊利诺伊大学理事会 2025-01-10 — — CN disclosed
US-20240409524-A1 COMPOUND HAVING PHOTOCLEAVABLE MOIETY, CONJUGATE, AND SCREENING METHOD USING SAME CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-12-12 — — US disclosed
EP-4378944-A1 COMPOUND HAVING PHOTOCLEAVABLE SITE, LINKER, AND SCREENING METHOD USING SAME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-06-05 — — EP disclosed
CN-117980308-A Compound having photocleavable site, joined body, and screening method using same 中外制药株式会社 2024-05-03 — — CN disclosed
US-20240117402-A1 METHODS FOR (POLY) PEPTIDE TANDEM LIGATION AND CYCLIZATION NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2024-04-11 — — US disclosed
EP-4291674-A1 METHODS FOR (POLY) PEPTIDE TANDEM LIGATION AND CYCLIZATION Nanyang Technological University (SG) 2023-12-20 — — EP disclosed
US-20230365656-A1 A FUSION PROTEIN THE UNIVERSITY OF QUEENSLAND (NZ) 2023-11-16 — — US disclosed
WO-2023054636-A1 COMPOUND HAVING PHOTOCLEAVABLE SITE, LINKER, AND SCREENING METHOD USING SAME 中外製薬株式会社 2023-04-06 — — WO disclosed
EP-4153209-A1 METHOD FOR TREATING LYSOSOMAL STORAGE DISEASES WITH HISTATIN PEPTIDES The Board of Trustees of the University of Illinois (US) 2023-03-29 — — EP disclosed
US-20230027620-A1 PENTAPEPTIDE AND METHODS OF USE THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2023-01-26 — — US disclosed
EP-4065171-A1 PENTAPEPTIDE AND METHODS OF USE THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2022-10-05 — — EP disclosed
WO-2022173377-A1 METHODS FOR (POLY) PEPTIDE TANDEM LIGATION AND CYCLIZATION NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-08-18 — — WO disclosed
CN-108602852-B Histamine and methods of use thereof 伊利诺伊大学理事会 2022-07-22 — — CN disclosed
CN-114746121-A Pentapeptides and methods of use thereof 伊利诺伊大学理事会 2022-07-12 — — CN disclosed
US-11370816-B2 Histatins and method of use thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2022-06-28 — — US disclosed
CN-106459160-B ASX-specific protein ligases 南洋理工大学 2022-03-29 — — CN disclosed
EP-3941485-A1 ANTIGEN BINDING PROTEINS Bio-Rad ABD Serotec GmbH (DE) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409524-A1 COMPOUND HAVING PHOTOCLEAVABLE MOIETY, CONJUGATE, AND SCREENING METHOD USING SAME ALDH1A2, FOLH1, TACR1 BACE1 1578/4885OPRD1 1993/4885CTSD 1535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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