Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 18/20 | 0.85 |
| ▸ | MEN1 | O00255 | 2/20 | 0.85 |
| ▸ | LMNA | P02545 | 2/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.85 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.85 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.85 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.85 |
| ▸ | MAPT | P10636 | 1/20 | 0.85 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.85 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.85 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.85 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.85 |
| ▸ | DRD3 | P35462 | 1/20 | 0.85 |
| ▸ | HTR2B | P41595 | 1/20 | 0.85 |
| ▸ | BLM | P54132 | 1/20 | 0.85 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Apovincamine SCHEMBL194507 | 1.00 | PDE1A (0.85) | PDE1AMEN1LMNAKMT2AHIF1A | |
| Apovincamine SCHEMBL10574604 | 1.00 | PDE1A (0.85) | PDE1AMEN1LMNAKMT2AHIF1A | |
| Apovincamine SCHEMBL10571224 | 1.00 | PDE1A (0.85) | PDE1AMEN1LMNAKMT2AHIF1A | |
| Apovincamine SCHEMBL11621460 | 0.96 | PDE1A (0.79) | PDE1AMEN1LMNAKMT2AHIF1A | |
| Apovincamine SCHEMBL11619316 | 0.95 | PDE1A (0.77) | PDE1AMEN1LMNAKMT2AHIF1A | |
| Apovincamine SCHEMBL11619228 | 0.92 | PDE1A (0.72) | PDE1AMEN1LMNAKMT2AHIF1A | |
| Apovincamine SCHEMBL11619498 | 0.92 | PDE1A (0.72) | PDE1AMEN1LMNAKMT2AHIF1A | |
| Apovincamine SCHEMBL11619109 | 0.92 | PDE1A (0.72) | PDE1AMEN1LMNAKMT2AHIF1A | |
| Vinpocetine SCHEMBL7947532 | 0.92 | PDE1A (1.00) | PDE1AMEN1LMNAKMT2AHIF1A | |
| Vinpocetine SCHEMBL21098929 | 0.92 | PDE1A (1.00) | PDE1AMEN1LMNAKMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119410679-A | Method for optimizing antibody expression | AMBRX公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119410678-A | Method for optimizing antibody expression | AMBRX公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-112313336-B | Method for optimizing antibody expression | AMBRX公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-114269749-B | 5H-pyrrolo [3,2-d ] pyrimidine-2, 4-diamino compounds and antibody conjugates thereof | 苏特罗生物制药公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-111655726-B | Antifolate receptor alpha antibody conjugates and uses thereof | 苏特罗生物制药公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-110078814-B | Modified FGF-21 polypeptides and uses thereof | 百时美施贵宝公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-115916811-A | Human interleukin-2 conjugates biased for interleukin-2 receptor beta gammac dimers conjugated with non-peptide water-soluble polymers | 默沙东有限责任公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114853868-A | Modified FGF-21 polypeptides and uses thereof | 百时美施贵宝公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114805531-A | Modified FGF-21 polypeptides and uses thereof | 百时美施贵宝公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805532-A | Modified FGF-21 polypeptides and uses thereof | 百时美施贵宝公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114796520-A | anti-CD 74 antibody conjugates, compositions comprising anti-CD 74 antibody conjugates, and methods of use of anti-CD 74 antibody conjugates | 苏特罗生物制药公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805533-A | Modified FGF-21 polypeptides and uses thereof | 百时美施贵宝公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114746420-A | 1- (4- (aminomethyl) benzyl) -2-butyl-2H-pyrazolo [3,4-c ] quinolin-4-amine derivatives as Toll-like receptor (TLR)7/8 agonists and related compounds and antibody drug conjugates thereof for cancer therapy and diagnosis | 苏特罗生物制药公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-109069664-B | anti-CD 74 antibody conjugates, compositions comprising anti-CD 74 antibody conjugates, and methods of use of anti-CD 74 antibody conjugates | 苏特罗生物制药公司 | 2022-05-13 | — | — | CN | disclosed |
| EP-3980080-A1 | IMMUNOMODULATOR ANTIBODY DRUG CONJUGATES AND USES THEREOF | Sutro Biopharma, Inc. (US) | 2022-04-13 | — | — | EP | disclosed |
| CN-114269749-A | 5H-pyrrolo [3,2-d ] pyrimidine-2, 4-diamino compounds and antibody conjugates thereof | 苏特罗生物制药公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114206392-A | Immunomodulatory agent antibody drug conjugates and uses thereof | 苏特罗生物制药公司 | 2022-03-18 | — | — | CN | disclosed |