SCHEMBL29421959

SCHEMBL29421959

CC(C)C[C@H](NC(=O)CN)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 2/20 0.51
▸ REN P00797 1/20 0.44
▸ NTSR1 P30989 4/20 0.43
▸ NTSR2 O95665 2/20 0.43
▸ OPRM1 P35372 6/20 0.42
▸ OPRK1 P41145 6/20 0.42
▸ OPRD1 P41143 1/20 0.42
▸ MMP1 P03956 1/20 0.42
▸ MMP3 P08254 1/20 0.42
▸ F2 P00734 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30933096 0.93 APLNR (0.51) APLNRRENNTSR1NTSR2OPRM1
SCHEMBL30933095 0.93 APLNR (0.54) APLNRRENNTSR1OPRM1OPRK1
SCHEMBL29421949 0.92 APLNR (0.49) APLNRRENNTSR1NTSR2OPRD1
SCHEMBL30933156 0.92 APLNR (0.53) APLNRRENNTSR1OPRD1
SCHEMBL30170451 0.92 APLNR (0.53) APLNRRENNTSR1OPRD1
SCHEMBL30933143 0.92 APLNR (0.53) APLNRRENNTSR1OPRD1
SCHEMBL29904095 0.92 APLNR (0.48) APLNRRENNTSR1NTSR2OPRD1
SCHEMBL30933107 0.91 APLNR (0.51) APLNRRENOPRM1OPRK1OPRD1
SCHEMBL30933116 0.90 APLNR (0.51) APLNRRENOPRM1OPRK1OPRD1
SCHEMBL30933141 0.90 APLNR (0.51) APLNRRENOPRM1OPRK1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 — — US claimed
EP-4114430-A2 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU Pharma, Inc. (KR) 2023-01-11 — — EP claimed
EP-3974441-A1 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2022-03-30 — — EP claimed
US-12428446-B2 Peptide compound or pharmaceutically acceptable salt thereof EYEBIO KOREA (KR) 2025-09-30 — — US disclosed
EP-4483959-A2 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2025-01-01 — — EP disclosed
EP-3974441-B1 PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2024-12-04 — — EP disclosed
US-20240352071-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof EYEBIO KOREA (KR) 2024-10-24 — — US disclosed
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof EYEBIO KOREA (KR) 2024-07-11 — — US disclosed
EP-3974441-A1 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2022-03-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428446-B2 Peptide compound or pharmaceutically acceptable salt thereof VIP, FURIN, IAPP APLNR 201/4885REN 38/4885NTSR1 170/4885
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof VIP, NPPA, NGLY1 APLNR 228/4885REN 35/4885NTSR1 215/4885
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 APLNR 334/4885REN 1013/4885NTSR1 1091/4885
US-20240352071-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof VIP, NPPA, NGLY1 APLNR 228/4885REN 35/4885NTSR1 215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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