SCHEMBL29421978

SCHEMBL29421978

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 1/20 0.51
▸ NTSR1 P30989 3/20 0.48
▸ NTSR2 O95665 1/20 0.48
▸ OPRD1 P41143 5/20 0.47
▸ F2 P00734 1/20 0.44
▸ REN P00797 1/20 0.44
▸ OPRM1 P35372 1/20 0.44
▸ OPRK1 P41145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29422008 0.97 APLNR (0.53) APLNRNTSR1NTSR2OPRD1OPRM1
SCHEMBL29421924 0.97 APLNR (0.49) APLNRNTSR1NTSR2OPRD1REN
SCHEMBL22380749 0.94 APLNR (0.52) APLNRNTSR1NTSR2OPRD1REN
SCHEMBL30933143 0.93 APLNR (0.53) APLNRNTSR1OPRD1REN
SCHEMBL30933156 0.93 APLNR (0.53) APLNRNTSR1OPRD1REN
SCHEMBL30170451 0.93 APLNR (0.53) APLNRNTSR1OPRD1REN
SCHEMBL30933096 0.92 APLNR (0.51) APLNRNTSR1NTSR2OPRD1REN
SCHEMBL30933116 0.91 APLNR (0.51) APLNROPRD1RENOPRM1OPRK1
SCHEMBL29421949 0.91 APLNR (0.49) APLNRNTSR1NTSR2OPRD1F2
SCHEMBL30933099 0.91 APLNR (0.51) APLNROPRD1RENOPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4483959-A2 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2025-01-01 — — EP disclosed
EP-3974441-B1 PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2024-12-04 — — EP disclosed
US-20240352071-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof EYEBIO KOREA (KR) 2024-10-24 — — US disclosed
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof EYEBIO KOREA (KR) 2024-07-11 — — US disclosed
EP-3974441-A1 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2022-03-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof VIP, NPPA, NGLY1 APLNR 228/4885NTSR1 215/4885NTSR2 194/4885
US-20240352071-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof VIP, NPPA, NGLY1 APLNR 228/4885NTSR1 215/4885NTSR2 194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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