SCHEMBL29421982

SCHEMBL29421982

NC(=O)CC[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 1/20 0.40
▸ KEAP1 Q14145 5/20 0.39
▸ CALCRL Q16602 1/20 0.37
▸ BMP1 P13497 1/20 0.36
▸ GLO1 Q04760 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ PRCP P42785 2/20 0.34
▸ CCKBR P32239 5/20 0.34
▸ PTGS1 P23219 1/20 0.34
▸ GSTK1 Q9Y2Q3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018582 0.91 PRCP (0.40) TERTKEAP1BMP1GLO1MEN1
SCHEMBL29421961 0.90 KEAP1 (0.44) TERTKEAP1CALCRLMEN1KMT2A
SCHEMBL29421977 0.88 KEAP1 (0.44) TERTKEAP1CALCRL
SCHEMBL30930148 0.87 MEN1 (0.41) TERTKEAP1BMP1MEN1KMT2A
SCHEMBL30930169 0.87 MEN1 (0.41) TERTKEAP1BMP1MEN1KMT2A
SCHEMBL30824015 0.87 NMT1 (0.44) KEAP1
SCHEMBL29630716 0.86 DPP7 (0.38) TERTKEAP1BMP1GLO1MEN1
SCHEMBL29517049 0.86 DPP7 (0.41) TERTGLO1MEN1KMT2APRCP
SCHEMBL29485647 0.86 KEAP1 (0.43) TERTKEAP1MEN1KMT2A
SCHEMBL22922937 0.85 KEAP1 (0.40) TERTKEAP1CALCRL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12428446-B2 Peptide compound or pharmaceutically acceptable salt thereof EYEBIO KOREA (KR) 2025-09-30 — — US disclosed
EP-4483959-A2 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2025-01-01 — — EP disclosed
EP-3974441-B1 PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2024-12-04 — — EP disclosed
US-20240352071-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof EYEBIO KOREA (KR) 2024-10-24 — — US disclosed
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof EYEBIO KOREA (KR) 2024-07-11 — — US disclosed
EP-3974441-A1 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2022-03-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428446-B2 Peptide compound or pharmaceutically acceptable salt thereof VIP, FURIN, IAPP TERT 3874/4885KEAP1 2728/4885CALCRL 423/4885
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof VIP, NPPA, NGLY1 TERT 4142/4885KEAP1 3089/4885CALCRL 456/4885
US-20240352071-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof VIP, NPPA, NGLY1 TERT 4142/4885KEAP1 3089/4885CALCRL 456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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