SCHEMBL2942237

SCHEMBL2942237

C[Si](C)(C)NC(=O)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636380 0.89
SCHEMBL1950611 0.77
SCHEMBL11136972 0.74
SCHEMBL19409131 0.74
SCHEMBL28614382 0.72
SCHEMBL28891868 0.70
SCHEMBL10583505 0.70 ALDH1A1 (0.32)
SCHEMBL6670710 0.69 EPHX1 (0.41)
SCHEMBL382216 0.69 TDP1 (0.39)
SCHEMBL11136321 0.69 TSHR (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11952324-B2 Amidoamine synthesis, methods to track the reaction process SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2024-04-09 US claimed
WO-2023141593-A2 PROCESS FOR SYNTHESIS OF GALBULIMIMA ALKALOID 18 AND COMPOUNDS USEFUL AS OPIOID RECEPTOR ANTAGONISTS AND AGONISTS THE SCRIPPS RESEARCH INSTITUTE (US) 2023-07-27 WO claimed
US-20210323909-A1 Amidoamine Synthesis, Methods to Track The Reaction Process SCHLUMBERGER TECHNOLOGY CORPORATION 2021-10-21 US claimed
US-20180148416-A1 INDUSTRIAL PROCESS FOR THE PREPARATION OF ENZALUTAMIDE OLON S.P.A. (IT) 2018-05-31 US claimed
US-9605019-B2 Methods for the synthesis of functionalized nucleic acids WAVE LIFE SCIENCES LTD. (SG) 2017-03-28 US claimed
EP-2467027-B1 PROCESS FOR COMPRESSING ISOMALT CARGILL INC (US) 2017-03-01 EP claimed
EP-2734208-B1 METHODS FOR THE SYNTHESIS OF FUNCTIONALIZED NUCLEIC ACIDS WAVE LIFE SCIENCES LTD (SG) 2017-03-01 EP claimed
US-20170029457-A1 METHODS FOR THE SYNTHESIS OF FUNCTIONALIZED NUCLEIC ACIDS WAVE LIFE SCIENCES LTD. (SG) 2017-02-02 US claimed
US-20150325458-A1 METHOD AND SYSTEM TO IMPROVE DRYING OF FLEXIBLE NANO-STRUCTURES TOKYO ELECTRON LIMITED (JP) 2015-11-12 US claimed
US-20140194610-A1 METHODS FOR THE SYNTHESIS OF FUNCTIONALIZED NUCLEIC ACIDS WAVE LIFE SCIENCES PTE. LTD. (SG) 2014-07-10 US claimed
US-7714148-B2 Process for the preparation of liquid, storage-stable organic isocyanates containing carbodiimide and/or uretoneimine groups BAYER MATERIALSCIENCE AG (DE) 2010-05-11 US claimed
EP-1971623-B1 METHOD FOR PRODUCING LIQUID, STORAGE-STABLE ORGANIC ISOCYANATES COMPRISING CARBODIIMIDE AND/OR URETONIMINE GROUPS BAYER MATERIALSCIENCE AG (DE) 2009-09-16 EP claimed
US-20070155939-A1 Process for the preparation of liquid, storage-stable organic isocyanates containing carbodiimide and/or uretoneimine groups BAYER MATERIALSCIENCE AG 2007-07-05 US claimed
US-5892008-A Process for the preparation of 6-O-methyl erythromycin a using 9-hydroxy erythromycin derivatives ABBOTT LABORATORIES (US) 1999-04-06 US claimed
EP-0500137-A1 1,2,4-Triazolo[1,5-a]pyrimidine derivatives, a process for preparing them as well as medicaments containing them and the use of them EGIS GYOGYSZERGYAR (HU) 1992-08-26 EP claimed
EP-0034394-B1 PROCESS FOR THE PREPARATION OF 3'-BROMOSUBSTITUTED DEACETOXYCEPHALOSPORANIC ACID SULPHOXIDE DERIVATIVES GIST-BROCADES N.V. (NL) 1984-08-01 EP claimed
US-4366315-A Process for preparing 3'bromo-desacetoxycephalosporanic acid sulfoxide compounds GIST-BROCADES N.V. (NL) 1982-12-28 US claimed
EP-0034394-A2 Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives GIST-BROCADES N.V. (NL) 1981-08-26 EP claimed
EP-3728590-B1 NOVEL THIOPHOSPHORAMIDITES ROCHE INNOVATION CT COPENHAGEN AS (DK) 2025-07-02 EP disclosed
EP-0034394-A2 Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives GIST-BROCADES N.V. (NL) 1981-08-26 EP disclosed