SCHEMBL11136972

SCHEMBL11136972

CNC(=O)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23926414 0.76 MGAM (0.35)
SCHEMBL2942237 0.74
SCHEMBL28614382 0.74
SCHEMBL10583505 0.72 ALDH1A1 (0.32)
SCHEMBL28891868 0.72
SCHEMBL28797163 0.72 CHRM2 (0.32)
SCHEMBL30697432 0.71 EPHX1 (0.35)
SCHEMBL6670710 0.70 EPHX1 (0.41)
SCHEMBL6645773 0.69 CHRNB2 (0.37)
SCHEMBL22556307 0.69 CA2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0017170-B1 IMPROVED PROCESS FOR THE PREPARATION OF CEPHAMYCIN ANTIBIOTICS MERCK & CO. INC. (US) 1983-04-13 EP claimed
EP-0017170-A1 Improved process for the preparation of cephamycin antibiotics MERCK & CO. INC. (US) 1980-10-15 EP claimed
US-4218563-A TRANSACYLATION IN PRESENCE OF N-TRIMETHYLSILYL LOWER ALKYL CARBAMATES MERCK & CO., INC. (US) 1980-08-19 US claimed
CN-102113153-B Sodium rechargeable battery SUMITOMO CHEMICAL CO 2013-11-20 CN disclosed
CN-102113153-A Sodium rechargeable battery SUMITOMO CHEMICAL CO 2011-06-29 CN disclosed
EP-0017170-B1 IMPROVED PROCESS FOR THE PREPARATION OF CEPHAMYCIN ANTIBIOTICS MERCK & CO. INC. (US) 1983-04-13 EP disclosed
EP-0017170-A1 Improved process for the preparation of cephamycin antibiotics MERCK & CO. INC. (US) 1980-10-15 EP disclosed
US-4220762-A Process for the preparation of cephamycin antibiotics MERCK & CO., INC. (US) 1980-09-02 US disclosed
US-4218563-A TRANSACYLATION IN PRESENCE OF N-TRIMETHYLSILYL LOWER ALKYL CARBAMATES MERCK & CO., INC. (US) 1980-08-19 US disclosed