Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | HPD | P32754 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29423928 | 1.00 | FFAR1 (0.42) | FFAR1HPDSCN3AKAT6AALOX5AP | |
| SCHEMBL18959380 | 0.89 | FFAR1 (0.42) | FFAR1HPDSCN3ACACNA1CKCNH2 | |
| SCHEMBL18940279 | 0.87 | FFAR1 (0.46) | FFAR1HPDSCN3AALOX5APKCNH2 | |
| SCHEMBL18940272 | 0.87 | FFAR1 (0.46) | FFAR1HPDSCN3AALOX5APKCNH2 | |
| SCHEMBL29423934 | 0.84 | FFAR1 (0.35) | FFAR1KAT6APOLB | |
| SCHEMBL16846001 | 0.84 | FFAR1 (0.35) | FFAR1KAT6APOLB | |
| SCHEMBL29423909 | 0.83 | MAOB (0.47) | FFAR1 | |
| SCHEMBL18963528 | 0.83 | FFAR1 (0.37) | FFAR1SCN3ACACNA1C | |
| SCHEMBL16845952 | 0.83 | FFAR1 (0.38) | FFAR1SCN3ACACNA1CKCNH2 | |
| SCHEMBL29423898 | 0.83 | FFAR1 (0.38) | FFAR1SCN3ACACNA1CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974413-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2022-03-30 | — | — | EP | disclosed |