Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.47 |
| ▸ | MAOA | P21397 | 6/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18940297 | 0.86 | FFAR1 (0.50) | MAOBMAOAFFAR1PARP15PARP10 | |
| SCHEMBL29423893 | 0.84 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL16846002 | 0.84 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL29423919 | 0.84 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL29423928 | 0.83 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL29423905 | 0.83 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL1478108 | 0.83 | KDM1A (0.47) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12749434 | 0.83 | KDM1A (0.47) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1478110 | 0.83 | KDM1A (0.47) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL15085312 | 0.81 | POLB (0.45) | MAOBFFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974413-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2022-03-30 | — | — | EP | disclosed |