Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16846001 | 1.00 | FFAR1 (0.35) | FFAR1KAT6AKDM4ETSHRALDH1A1 | |
| SCHEMBL18940278 | 0.88 | FFAR1 (0.41) | FFAR1KAT6AHPGDFFAR4POLB | |
| SCHEMBL13222719 | 0.85 | FFAR1 (0.36) | FFAR1KAT6AKDM4ETSHRALDH1A1 | |
| SCHEMBL29423905 | 0.84 | FFAR1 (0.42) | FFAR1KAT6APOLB | |
| SCHEMBL29423928 | 0.84 | FFAR1 (0.42) | FFAR1KAT6APOLB | |
| SCHEMBL16845971 | 0.83 | FFAR1 (0.34) | FFAR1KDM4ETSHRALDH1A1POLB | |
| SCHEMBL29423927 | 0.83 | FFAR1 (0.34) | FFAR1KDM4ETSHRALDH1A1POLB | |
| SCHEMBL9903728 | 0.81 | SMN1; SMN2 (0.38) | FFAR1KDM4ETSHRALDH1A1HPGD | |
| SCHEMBL18959380 | 0.80 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL29423909 | 0.79 | MAOB (0.47) | FFAR1ALDH1A1FFAR4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974413-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2022-03-30 | — | — | EP | disclosed |