Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16845971 | 1.00 | FFAR1 (0.34) | FFAR1UCHL1ALDH1A1KDM4EPOLB | |
| SCHEMBL18940277 | 0.90 | FFAR1 (0.42) | FFAR1POLB | |
| SCHEMBL29423898 | 0.85 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL29423910 | 0.85 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL16845952 | 0.85 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL29423934 | 0.83 | FFAR1 (0.35) | FFAR1ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL16846001 | 0.83 | FFAR1 (0.35) | FFAR1ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL16846002 | 0.80 | FFAR1 (0.41) | FFAR1POLB | |
| SCHEMBL29423919 | 0.80 | FFAR1 (0.41) | FFAR1POLB | |
| SCHEMBL29423893 | 0.80 | FFAR1 (0.41) | FFAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974413-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2022-03-30 | — | — | EP | disclosed |