Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 18/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | BRD4 | O60885 | 2/20 | 1.00 |
| ▸ | BRD2 | P25440 | 2/20 | 1.00 |
| ▸ | BRD3 | Q15059 | 2/20 | 1.00 |
| ▸ | PIK3CD | O00329 | 1/20 | 1.00 |
| ▸ | PDE2A | O00408 | 1/20 | 1.00 |
| ▸ | PIK3C2A | O00443 | 1/20 | 1.00 |
| ▸ | PIK3R2 | O00459 | 1/20 | 1.00 |
| ▸ | PIK3C2B | O00750 | 1/20 | 1.00 |
| ▸ | PDE5A | O76074 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | PIM1 | P11309 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ly-294002 SCHEMBL94377 | 1.00 | PRKDC (1.00) | PRKDCALDH1A1KDM4ESMN1; SMN2BRD4 | |
| Ly-294002 SCHEMBL5078472 | 0.99 | ALDH1A1 (1.00) | PRKDCALDH1A1KDM4ESMN1; SMN2BRD4 | |
| SCHEMBL13496867 | 0.99 | PRKDC (0.97) | PRKDCALDH1A1KDM4ESMN1; SMN2BRD4 | |
| SCHEMBL31061056 | 0.95 | PRKDC (1.00) | PRKDCALDH1A1KDM4ESMN1; SMN2BRD4 | |
| SCHEMBL14041172 | 0.94 | PRKDC (1.00) | PRKDCALDH1A1KDM4ESMN1; SMN2BRD4 | |
| SCHEMBL5261685 | 0.90 | PRKDC (0.81) | PRKDCALDH1A1KDM4ESMN1; SMN2BRD4 | |
| SCHEMBL5260468 | 0.90 | PRKDC (0.81) | PRKDCALDH1A1KDM4ESMN1; SMN2BRD4 | |
| SCHEMBL4423159 | 0.90 | PRKDC (0.81) | PRKDCALDH1A1KDM4ESMN1; SMN2BRD4 | |
| SCHEMBL31060584 | 0.89 | PRKDC (1.00) | PRKDCALDH1A1KDM4ESMN1; SMN2BRD4 | |
| SCHEMBL13700043 | 0.89 | PRKDC (0.80) | PRKDCALDH1A1KDM4ESMN1; SMN2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561704-A2 | USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER | The University Of Vermont (US) | 2025-06-04 | — | — | EP | claimed |
| WO-2025054356-A1 | BET INHIBITORS FOR THE TREATMENT OF CANCER | LEAPFROG BIO, INC. (US) | 2025-03-13 | — | — | WO | claimed |
| EP-4333822-A1 | COMPOSITION COMPRISING AN INHIBITOR OF MITOCHONDRIAL TRANSCRIPTION | Lead Discovery Center GmbH (DE) | 2024-03-13 | — | — | EP | claimed |
| WO-2024026458-A2 | USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER | THE UNIVERSITY OF VERMONT (US) | 2024-02-01 | — | — | WO | claimed |
| EP-4110344-A2 | USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER | The University Of Vermont (US) | 2023-01-04 | — | — | EP | claimed |
| WO-2022233782-A1 | COMPOSITION COMPRISING AN INHIBITOR OF MITOCHONDRIAL TRANSCRIPTION | LEAD DISCOVERY CENTER GMBH (DE) | 2022-11-10 | — | — | WO | claimed |
| WO-2025262235-A1 | UNGULATE PLURIPOTENT STEM CELL CULTURE MEDIUM | MEAT TOMORROW APS (DK) | 2025-12-26 | — | — | WO | disclosed |
| EP-4561704-A2 | USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER | The University Of Vermont (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-119606949-A | Protection effect of costunolide on neonatal rat hypoxic ischemic brain injury | 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） | 2025-03-14 | — | — | CN | disclosed |
| CN-118234496-A | Improved treatment of advanced/metastatic cancers with checkpoint inhibitor resistance or drug resistance susceptibility | 海南先声再明医药股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| EP-4333822-A1 | COMPOSITION COMPRISING AN INHIBITOR OF MITOCHONDRIAL TRANSCRIPTION | Lead Discovery Center GmbH (DE) | 2024-03-13 | — | — | EP | disclosed |
| WO-2024026458-A2 | USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER | THE UNIVERSITY OF VERMONT (US) | 2024-02-01 | — | — | WO | disclosed |
| CN-117384809-A | Tumor targeting engineering bacterium capable of secreting protein in situ, construction method and application thereof | 中山大学·深圳 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022169684-A1 | METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING RARE GENETIC DISEASES | ROSEBUD BIOSCIENCES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| WO-2022140776-A1 | METHODS AND COMPOSITIONS COMPRISING TUMOR SUPPRESSOR GENE THERAPY FOR THE INHIBITION OF PATHOGENS | MULTIVIR INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| CN-114585368-A | Application of albiflorin or paeoniflorin in preventing and/or treating renal anemia | 张作光 | 2022-06-03 | — | — | CN | disclosed |
| WO-2022115865-A2 | TUMOR-SPECIFIC CLEAVABLE LINKERS | Xilio Development, Inc. (US) | 2022-06-02 | — | — | WO | disclosed |
| EP-3980541-A1 | APTAMERS AGAINST TRANSFERRIN RECEPTOR (TFR) | Apterna Limited (GB) | 2022-04-13 | — | — | EP | disclosed |
| EP-3973049-A1 | METHODS OF CULTURING HUMAN PLURIPOTENT CELLS | Hadasit Medical Research Services and Development Ltd. (IL) | 2022-03-30 | — | — | EP | disclosed |
| WO-2022046682-A1 | BROMODOMAIN AND EXTRA TERMINAL DOMAIN (BET) INHIBITOR COMPOSITIONS AND METHODS THEREOF FOR USE AS ANTI-AGING AGENTS | MDI BIOLOGICAL LABORATORY (US) | 2022-03-03 | — | — | WO | disclosed |