Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.60 |
| ▸ | PRKCI | P41743 | 3/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298491 | 1.00 | BRD4 (0.60) | BRD4PRKCIAXLAURKBIKBKB | |
| SCHEMBL30669883 | 0.84 | BRD4 (0.52) | BRD4PRKCIAXLAURKBIKBKB | |
| SCHEMBL2992617 | 0.81 | NUDT1 (0.55) | BRD4PRKCIAXLAURKBIKBKB | |
| SCHEMBL12605521 | 0.81 | CCNK (0.51) | BRD4PRKCIAXLAURKBIKBKB | |
| SCHEMBL2986157 | 0.80 | CIT (0.50) | BRD4PRKCIAXLAURKBIKBKB | |
| SCHEMBL30461709 | 0.79 | NUDT1 (0.52) | BRD4PRKCIAXLAURKBIKBKB | |
| SCHEMBL2988049 | 0.79 | NUDT1 (0.52) | BRD4PRKCIAXLAURKBIKBKB | |
| SCHEMBL10125070 | 0.79 | BRD4 (0.66) | BRD4PRKCIAURKBIKBKBCHUK | |
| SCHEMBL858602 | 0.79 | BRD4 (0.62) | BRD4PRKCIAURKBIKBKBCHUK | |
| SCHEMBL29120136 | 0.78 | PRKCI (0.50) | BRD4PRKCIAXLAURKBIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974044-A | Compounds of formula (I) | 赛洛私人有限公司 | 2024-11-15 | — | — | CN | disclosed |
| US-20240034799-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | CEDARS SINAI MEDICAL CENTER (US) | 2024-02-01 | — | — | US | disclosed |
| US-20230279491-A1 | TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER | 2023-09-07 | — | — | US | disclosed |
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114040915-A | Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors | 里伯赛恩斯有限责任公司 | 2022-02-11 | — | — | CN | disclosed |