Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900980 | 1.00 | MAPK1 (0.48) | MAPK1KDM4EL3MBTL1CRBNRAB9A | |
| SCHEMBL2713417 | 0.91 | GPR119 (0.43) | MAPK1KDM4EL3MBTL1ATRSSTR3 | |
| SCHEMBL2391034 | 0.89 | AKT1 (0.36) | MAPK1CRBNAKT1KITMAPT | |
| SCHEMBL2712872 | 0.89 | HCAR3 (0.42) | MAPK1KDM4EL3MBTL1MAPT | |
| SCHEMBL27077996 | 0.86 | MAPK1 (0.38) | MAPK1KDM4EL3MBTL1CRBNRAB9A | |
| SCHEMBL2732023 | 0.85 | KIT (0.36) | L3MBTL1AKT1KITMAPT | |
| SCHEMBL12802803 | 0.84 | KIT (0.35) | AKT1KIT | |
| SCHEMBL22615478 | 0.83 | MAPK1 (0.41) | MAPK1KDM4EL3MBTL1CRBNRAB9A | |
| SCHEMBL29730109 | 0.83 | MAPK1 (0.43) | MAPK1KDM4EL3MBTL1CRBNRAB9A | |
| SCHEMBL27202134 | 0.83 | MAPK1 (0.43) | MAPK1KDM4EL3MBTL1CRBNRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3962912-A1 | NOVEL PHENYL AND PYRIDYL UREAS ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV) | AiCuris GmbH & Co. KG (DE) | 2022-03-09 | — | — | EP | disclosed |
| EP-3962914-A1 | NOVEL INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV) | AiCuris GmbH & Co. KG (DE) | 2022-03-09 | — | — | EP | disclosed |