SCHEMBL29425313

SCHEMBL29425313

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCCN)C(C)C)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NTSR2 O95665 3/20 0.62
▸ NTSR1 P30989 3/20 0.62
▸ NPY4R P50391 4/20 0.56
▸ NPY1R P25929 3/20 0.56
▸ NPY2R P49146 3/20 0.56
▸ BACE1 P56817 10/20 0.56
▸ BACE2 Q9Y5Z0 4/20 0.56
▸ F2 P00734 2/20 0.54
▸ SORT1 Q99523 2/20 0.54
▸ NPY5R Q15761 2/20 0.53
▸ CTSD P07339 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30445824 0.94 NTSR2 (0.56) NTSR2NTSR1NPY4RNPY1RNPY2R
SCHEMBL31031460 0.89 NPY4R (0.54) NTSR2NTSR1NPY4RNPY1RNPY2R
SCHEMBL29770017 0.88 NTSR2 (0.68) NTSR2NTSR1NPY4RNPY1RNPY2R
SCHEMBL29447812 0.88 NTSR2 (0.69) NTSR2NTSR1NPY4RNPY1RNPY2R
SCHEMBL30784953 0.88 BACE1 (0.60) NPY4RNPY1RNPY2RBACE1BACE2
SCHEMBL30445421 0.88 NTSR2 (0.55) NTSR2NTSR1NPY4RNPY1RNPY2R
SCHEMBL29611893 0.87 NTSR1 (0.61) NTSR2NTSR1NPY4RNPY1RNPY2R
SCHEMBL30471450 0.87 NPY4R (0.69) NTSR2NTSR1NPY4RNPY1RNPY2R
SCHEMBL31405782 0.87 BACE1 (0.55) NTSR2NTSR1BACE1BACE2F2
SCHEMBL30462190 0.87 NPY4R (0.72) NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132183-A1 T CELL RECEPTORS DIRECTED AGAINST MELANOMA-ASSOCIATED ANTIGEN AND USES THEREOF ACAD ZIEKENHUIS LEIDEN H O D N LUMC (NL) 2026-05-14 — — US claimed
US-20250367276-A1 MICROBIOTA ANALOGS OF TUMOR ASSOCIATED ANTIGENS AND USES THEREOF ISTITUTO NAZIONALE TUMORI IRCCS - FONDAZIONE G. PASCALE (IT) 2025-12-04 — — US claimed
US-20250269002-A1 CTA VACCINE CASSETTES GRITSTONE BIO INC (US) 2025-08-28 — — US claimed
EP-4565264-A2 CTA VACCINE CASSETTES Gritstone bio, Inc. (US) 2025-06-11 — — EP claimed
WO-2024031027-A9 CTA VACCINE CASSETTES GRITSTONE BIO, INC. (US) 2025-04-24 — — WO claimed
EP-4536703-A1 T CELL RECEPTORS DIRECTED AGAINST MELANOMA-ASSOCIATED ANTIGEN AND USES THEREOF Academisch Ziekenhuis Leiden (h.o.d.n. LUMC) (NL) 2025-04-16 — — EP claimed
EP-4534554-A1 MAGE-A1 SPECIFIC TCR AND USE THEREOF Corregene Biotechnology Co., Ltd. (CN) 2025-04-09 — — EP claimed
CN-119730873-A Microbial analogues of tumor associated antigens and uses thereof 国家癌症研究所IRCCS-G·帕斯卡莱基金会 2025-03-28 — — CN claimed
CN-119529098-A Binding molecules specific for MAGE-A1 and anti-CD 3 fusion proteins 北京可瑞生物科技有限公司 2025-02-28 — — CN claimed
EP-4504343-A1 MICROBIOTA ANALOGS OF TUMOR ASSOCIATED ANTIGENS AND USES THEREOF Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale (IT) 2025-02-12 — — EP claimed
WO-2023239241-A1 T CELL RECEPTORS DIRECTED AGAINST MELANOMA-ASSOCIATED ANTIGEN AND USES THEREOF ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) (NL) 2023-12-14 — — WO claimed
WO-2023232111-A1 MAGE-A1 SPECIFIC TCR AND USE THEREOF 北京可瑞生物科技有限公司 2023-12-07 — — WO claimed
WO-2023194549-A1 MICROBIOTA ANALOGS OF TUMOR ASSOCIATED ANTIGENS AND USES THEREOF ISTITUTO NAZIONALE TUMORI IRCCS - FONDAZIONE G. PASCALE (IT) 2023-10-12 — — WO claimed
US-20230192886-A1 ADOPTIVE CELL THERAPY COMBINATION TREATMENT AND COMPOSITIONS THEREOF IMMATICS BIOTECHNOLOGIES GMBH (DE) 2023-06-22 — — US claimed
WO-2023081925-A1 ADOPTIVE CELL THERAPY COMBINATION TREATMENT AND COMPOSITIONS THEREOF IMMATICS BIOTECHNOLOGIES GMBH (DE) 2023-05-11 — — WO claimed
US-20220370586-A1 METHOD OF GENERATING ACTIVATED T CELLS FOR CANCER THERAPY CEDARS-SINAI MEDICAL CENTER (US) 2022-11-24 — — US claimed
CN-115052885-A Specific binding molecules 英美偌科有限公司 2022-09-13 — — CN claimed
EP-4048684-A1 SPECIFIC BINDING MOLECULES Immunocore Limited (GB) 2022-08-31 — — EP claimed
EP-4010009-A2 METHOD OF GENERATING ACTIVATED T CELLS FOR CANCER THERAPY Cedars-Sinai Medical Center (US) 2022-06-15 — — EP claimed
WO-2022076353-A1 COMPOSITIONS AND METHODS FOR TREATING MAGE-A1-EXPRESSING DISEASE FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2022-04-14 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132183-A1 T CELL RECEPTORS DIRECTED AGAINST MELANOMA-ASSOCIATED ANTIGEN AND USES THEREOF MICA, CD74, TAP1 NTSR2 1601/4885NTSR1 513/4885NPY4R 2181/4885
US-20220370586-A1 METHOD OF GENERATING ACTIVATED T CELLS FOR CANCER THERAPY NFATC1, CD4, ICOS NTSR2 3440/4885NTSR1 2814/4885NPY4R 4609/4885
US-20250269002-A1 CTA VACCINE CASSETTES KRAS, TP53, TSG101 NTSR2 3345/4885NTSR1 2829/4885NPY4R 4595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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