Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31326252 | 1.00 | TERT (0.41) | TERTOPRD1OPRM1OPRK1MME | |
| SCHEMBL2555751 | 0.96 | TERT (0.43) | TERTOPRD1OPRM1OPRK1MME | |
| SCHEMBL29448560 | 0.93 | TERT (0.41) | TERTOPRD1OPRM1OPRK1MME | |
| SCHEMBL29454351 | 0.90 | ALDH1A1 (0.47) | TERTOPRD1OPRM1OPRK1MME | |
| SCHEMBL30099552 | 0.87 | ALDH1A1 (0.44) | TERTOPRD1OPRM1OPRK1MME | |
| SCHEMBL30099553 | 0.87 | ALDH1A1 (0.44) | TERTOPRD1OPRM1OPRK1MME | |
| SCHEMBL30546898 | 0.87 | ALDH1A1 (0.44) | TERTOPRD1OPRM1OPRK1MME | |
| SCHEMBL18342371 | 0.86 | SMN1; SMN2 (0.41) | OPRD1OPRM1OPRK1MMEACE | |
| SCHEMBL31194770 | 0.86 | SMN1; SMN2 (0.41) | OPRD1OPRM1OPRK1MMEACE | |
| SCHEMBL29425543 | 0.86 | SMN1; SMN2 (0.41) | OPRD1OPRM1OPRK1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3962518-A1 | IMMUNOGEN FOR PREVENTING OR TREATING FAMILIAL FRONTOTEMPORAL DEMENTIA (FTD) AND/OR AMYOTROPHIC LATERAL SCLEROSIS (ALS) | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) (DE) | 2022-03-09 | — | — | EP | disclosed |