Excelside A

Excelside A

SCHEMBL29425857

C/C=C1/C(O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)OC=C(C(=O)OC)[C@H]1CC(=O)OC

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ IL2 P60568 1/20 0.72
▸ BACE1 P56817 1/20 0.66
▸ MAPT P10636 2/20 0.63
▸ POLB P06746 2/20 0.63
▸ KDM4E B2RXH2 1/20 0.63
▸ GAA P10253 1/20 0.63
▸ NPSR1 Q6W5P4 1/20 0.63
▸ STAT3 P40763 13/20 0.51
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ CTDSP1 Q9GZU7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oleoside Dimethyl Ester SCHEMBL21324467 0.95 BACE1 (0.71) IL2BACE1MAPTPOLBKDM4E
Oleoside Dimethyl Ester SCHEMBL19831306 0.95 BACE1 (0.71) IL2BACE1MAPTPOLBKDM4E
Oleoside Dimethyl Ester SCHEMBL29425902 0.95 BACE1 (0.71) IL2BACE1MAPTPOLBKDM4E
SCHEMBL29426120 0.89 IL2 (0.71) IL2BACE1MAPTPOLBKDM4E
SCHEMBL29425896 0.89 IL2 (0.71) IL2BACE1MAPTPOLBKDM4E
SCHEMBL29426103 0.88 BACE1 (0.68) IL2BACE1MAPTPOLBKDM4E
SCHEMBL23494908 0.87 BACE1 (0.67) IL2BACE1MAPTPOLBKDM4E
SCHEMBL29425877 0.87 BACE1 (0.67) IL2BACE1MAPTPOLBKDM4E
SCHEMBL23521505 0.87 BACE1 (0.62) IL2BACE1MAPTPOLBKDM4E
SCHEMBL29426034 0.87 BACE1 (0.67) IL2BACE1MAPTPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702037-A1 METHOD OF PRODUCING IRIDOIDS Nicoventures Trading Limited (GB) 2026-03-04 — — EP disclosed
WO-2024224085-A1 METHOD OF PRODUCING IRIDOIDS Nicoventures Trading Limited (GB) 2024-10-31 — — WO disclosed
CN-109689077-B Novel use and method 纳图瑞克斯有限公司 2023-03-07 — — CN disclosed
US-11590189-B2 Therapeutic use of a Fraximus augustifolia extract NATUREX S.A. (FR) 2023-02-28 — — US disclosed
EP-3409766-B1 AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS N ZYME BIOTEC GMBH (DE) 2022-03-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11590189-B2 Therapeutic use of a Fraximus augustifolia extract FABP1, FXR1, FXR2 IL2 4744/4885BACE1 3193/4885MAPT 2927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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