Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | AMY2A | P04746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29425833 | 0.84 | PRKCA (0.51) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL9057809 | 0.83 | PRKCA (0.50) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL29426091 | 0.83 | CYP19A1 (0.44) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL29426041 | 0.82 | HSP90AA1 (0.46) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL29426143 | 0.80 | PRKCA (0.52) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL31179879 | 0.78 | HSP90AA1 (0.55) | PRKCAAKR1B1CYP3A4CA12CA4 | |
| SCHEMBL31179884 | 0.78 | HSP90AA1 (0.55) | PRKCAAKR1B1CYP3A4CA12CA4 | |
| SCHEMBL29425919 | 0.77 | PTPN1 (0.52) | CYP3A4CA12CA4CA7TYR | |
| Tarenninoside D SCHEMBL29426111 | 0.75 | PRKCA (0.46) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL29425865 | 0.75 | PTPN1 (0.49) | PRKCACYP19A1CYP3A4CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3409766-B1 | AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS | N ZYME BIOTEC GMBH (DE) | 2022-03-09 | — | — | EP | disclosed |