Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | AMY2A | P04746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tarenninoside F SCHEMBL29426269 | 0.87 | PRKCA (0.51) | PRKCACYP19A1PTPN1ELANESNCA | |
| Tarenninoside E SCHEMBL29426088 | 0.86 | PTPN1 (0.46) | PRKCACYP19A1PTPN1ELANE | |
| Tarenninoside C SCHEMBL29426155 | 0.86 | XDH (0.52) | PTPN1 | |
| SCHEMBL29426143 | 0.85 | PRKCA (0.52) | PRKCACYP19A1PTPN1MMP2MMP3 | |
| SCHEMBL29425919 | 0.81 | PTPN1 (0.52) | PTPN1ELANECA12CA4CA7 | |
| Tarenninoside A SCHEMBL29426059 | 0.80 | XDH (0.51) | PTPN1 | |
| SCHEMBL29425865 | 0.78 | PTPN1 (0.49) | PRKCACYP19A1PTPN1ELANECA12 | |
| SCHEMBL3366430 | 0.78 | MAOB (0.60) | PRKCACYP19A1MMP9MMP13MAOB | |
| SCHEMBL29425833 | 0.77 | PRKCA (0.51) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL24140171 | 0.76 | MAOB (0.61) | PRKCACYP19A1MMP9MMP13MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3409766-B1 | AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS | N ZYME BIOTEC GMBH (DE) | 2022-03-09 | — | — | EP | disclosed |