Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | AMY2A | P04746 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29426013 | 0.94 | SNCA (0.51) | PRKCAPTPN1HSP90AA1SNCAALDH1A1 | |
| SCHEMBL29425895 | 0.90 | HSP90AA1 (0.47) | PTPN1HSP90AA1SNCAALDH1A1CYP3A4 | |
| SCHEMBL29536623 | 0.80 | PTPN1 (0.61) | PRKCAPTPN1HSP90AA1SNCAALDH1A1 | |
| SCHEMBL29536291 | 0.80 | PTPN1 (0.61) | PRKCAPTPN1HSP90AA1SNCAALDH1A1 | |
| SCHEMBL29425893 | 0.78 | PRKCA (0.55) | PRKCAPTPN1HSP90AA1SNCAALDH1A1 | |
| SCHEMBL15438013 | 0.77 | SNCA (0.64) | PRKCAPTPN1SNCAALDH1A1CYP3A4 | |
| SCHEMBL15711514 | 0.76 | SNCA (0.66) | PRKCAPTPN1SNCAALDH1A1CYP3A4 | |
| SCHEMBL20944781 | 0.76 | SNCA (0.66) | PRKCAPTPN1SNCAALDH1A1CYP3A4 | |
| SCHEMBL546975 | 0.76 | SNCA (0.66) | PRKCAPTPN1SNCAALDH1A1CYP3A4 | |
| SCHEMBL17938787 | 0.75 | PTPN1 (0.58) | PRKCAPTPN1SNCAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3409766-B1 | AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS | N ZYME BIOTEC GMBH (DE) | 2022-03-09 | — | — | EP | disclosed |