SCHEMBL29425960

COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(C)=O)[C@H]2[C@@H]1[C@H](O)[C@H](O)[C@]2(C)O

nearest known ligand 0.53

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	POLB	P06746	1/20	0.53

▸	CTDSP1	Q9GZU7	1/20	0.53

▸	STAT3	P40763	14/20	0.47

▸	MEN1	O00255	1/20	0.45

▸	MAPT	P10636	1/20	0.45

▸	KMT2A	Q03164	1/20	0.45

▸	ELANE	P08246	1/20	0.42

▸	JUN	P05412	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Lamalbid SCHEMBL9056954	0.89	POLB (0.66)	POLBCTDSP1STAT3MEN1MAPT
Chlorotuberoside SCHEMBL29425799	0.80	POLB (0.62)	POLBCTDSP1STAT3MEN1MAPT
SCHEMBL29425733	0.79	MAPT (0.56)	POLBCTDSP1STAT3MEN1MAPT
SCHEMBL29827955	0.76	STAT3 (0.64)	STAT3MEN1MAPTKMT2A
Phlorigidoside C SCHEMBL29425891	0.76	POLB (0.61)	POLBCTDSP1STAT3MEN1MAPT
SCHEMBL14010694	0.75	POLB (0.39)	POLBCTDSP1STAT3MEN1MAPT
Shanzhiside Methyl Ester SCHEMBL29965826	0.75	POLB (0.62)	POLBCTDSP1STAT3MEN1MAPT
Shanzhiside Methyl Ester SCHEMBL12207355	0.75	POLB (0.62)	POLBCTDSP1STAT3MEN1MAPT
Shanzhiside Methyl Ester SCHEMBL28007134	0.75	POLB (0.62)	POLBCTDSP1STAT3MEN1MAPT
Barlerin SCHEMBL3244727	0.74	POLB (0.56)	POLBCTDSP1STAT3MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3409766-B1	AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS	N ZYME BIOTEC GMBH (DE)	2022-03-09	—	—	EP	disclosed