Dehydromethoxygaertneroside

Dehydromethoxygaertneroside

SCHEMBL29426153

COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]2[C@@H]1C=C[C@@]21C=C(C(=O)c2ccc(O)c(OC)c2)C(=O)O1

nearest known ligand 0.58

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Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.58
▸ CTDSP1 Q9GZU7 1/20 0.58
▸ JUN P05412 2/20 0.56
▸ MEN1 O00255 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ STAT3 P40763 11/20 0.42
▸ ELANE P08246 1/20 0.40
▸ PTPN1 P18031 1/20 0.40
▸ BACE1 P56817 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dehydromethoxygaertneroside SCHEMBL31180007 1.00 POLB (0.58) POLBCTDSP1JUNMEN1MAPT
Dehydrogaertneroside SCHEMBL29425897 0.90 POLB (0.62) POLBCTDSP1JUNMEN1MAPT
Methoxygaertneroside SCHEMBL29425775 0.85 POLB (0.56) POLBCTDSP1JUNMEN1MAPT
Methoxygaertneroside SCHEMBL29425771 0.85 POLB (0.56) POLBCTDSP1JUNMEN1MAPT
SCHEMBL29426062 0.84 JUN (0.66) POLBCTDSP1JUNMEN1MAPT
SCHEMBL29425686 0.82 POLB (0.68) POLBCTDSP1JUNMEN1MAPT
Plumieride SCHEMBL419720 0.80 POLB (0.65) POLBCTDSP1JUNMEN1MAPT
Gaertneroside SCHEMBL31179982 0.78 POLB (0.60) POLBCTDSP1JUNMEN1MAPT
Gaertneroside SCHEMBL420081 0.78 POLB (0.60) POLBCTDSP1JUNMEN1MAPT
Galioside SCHEMBL29431810 0.74 POLB (1.00) POLBCTDSP1JUNMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702037-A1 METHOD OF PRODUCING IRIDOIDS Nicoventures Trading Limited (GB) 2026-03-04 — — EP disclosed
EP-4626425-A1 TARGETING INNATE IMMUNE MEMORY AND AP-1 OR ATF3 FOR THE TREATMENT OF OCULAR DISEASES RSEM, Limited Partnership (CA) 2025-10-08 — — EP disclosed
WO-2025068418-A1 INHIBITOR OF THE TRANSCRIPTION FACTOR AP-1 FOR USE IN THE TREATMENT OF AGE-RELATED DISEASES Institut National de la Santé et de la Recherche Médicale (FR) 2025-04-03 — — WO disclosed
WO-2024224085-A1 METHOD OF PRODUCING IRIDOIDS Nicoventures Trading Limited (GB) 2024-10-31 — — WO disclosed
WO-2024113061-A1 TARGETING INNATE IMMUNE MEMORY AND AP-1 OR ATF3 FOR THE TREATMENT OF OCULAR DISEASES SAPIEHA PRZEMYSLAW (CA) 2024-06-06 — — WO disclosed
EP-3409766-B1 AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS N ZYME BIOTEC GMBH (DE) 2022-03-09 — — EP disclosed
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