SCHEMBL29426315

SCHEMBL29426315

CC1=C(C(=O)OCCN2C(=O)c3ccccc3S2(=O)=O)C(c2cccc([N+](=O)[O-])c2)C(C(=O)OCC2CCCCO2)=C(C)N1

nearest known ligand 0.88

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CACNA1F O60840 8/20 0.51
CACNA1D Q01668 8/20 0.51
CACNA1S Q13698 8/20 0.51
CACNA1C Q13936 8/20 0.51
KMT2A Q03164 1/20 0.48
POLB P06746 1/20 0.48
ADORA3 P0DMS8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194784 1.00 CACNA1F (0.51) CACNA1FCACNA1DCACNA1SCACNA1CKMT2A
SCHEMBL6955134 0.82 POLB (0.68) CACNA1FCACNA1DCACNA1SCACNA1CKMT2A
SCHEMBL7416441 0.79 POLB (0.64) CACNA1FCACNA1DCACNA1SCACNA1CKMT2A
SCHEMBL7132512 0.79 POLB (0.75) CACNA1FCACNA1DCACNA1SCACNA1CKMT2A
SCHEMBL7341750 0.76 CACNA1F (0.70) CACNA1FCACNA1DCACNA1SCACNA1CKMT2A
SCHEMBL10670264 0.75 KMT2A (0.76) CACNA1FCACNA1DCACNA1SCACNA1CKMT2A
SCHEMBL10666490 0.75 CACNA1F (0.57) CACNA1FCACNA1DCACNA1SCACNA1CKMT2A
SCHEMBL7274108 0.74 CACNA1F (0.75) CACNA1FCACNA1DCACNA1SCACNA1CKMT2A
SCHEMBL10918103 0.73 MAPT (0.70) CACNA1FCACNA1DCACNA1SCACNA1CKMT2A
SCHEMBL9675181 0.73 MEN1 (0.70) CACNA1FCACNA1DCACNA1SCACNA1CKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714407-A2 DEVICES TO PROVIDE HANDS FREE SCLERAL DEPRESSION DURING OPHTHALMIC PROCEDURES Alcon Inc. (CH) 2026-03-25 EP disclosed
EP-3157408-B1 DEVICES TO PROVIDE HANDS FREE SCLERAL DEPRESSION DURING OPHTHALMIC PROCEDURES ALCON INC (CH) 2026-03-25 EP disclosed
US-20250057694-A1 DEVICES AND METHODS TO PROVIDE HANDS FREE SCLERAL DEPRESSION AND ILLUMINATION DURING OPHTHALMIC PROCEDURES Ganihand, LLC (US) 2025-02-20 US disclosed
EP-3485881-B1 PERMANENTLY CHARGED SODIUM AND CALCIUM CHANNEL BLOCKERS AS ANTI-INFLAMMATORY AGENTS HARVARD COLLEGE (US) 2024-03-13 EP disclosed
US-20230165812-A1 NOCICEPTOR NEURONS CONTROL CANCER IMMUNOSURVEILLANCE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-06-01 US disclosed
US-11266395-B2 Devices and methods to provide hands free scleral depression during ophthalmic procedures Ganihand, LLC (US) 2022-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165812-A1 NOCICEPTOR NEURONS CONTROL CANCER IMMUNOSURVEILLANCE OPRL1, MRGPRX1, RAMP1 CACNA1F 82/4885CACNA1D 77/4885CACNA1S 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.