Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | CACNA1F | O60840 | 9/20 | 0.63 |
| ▸ | CACNA1D | Q01668 | 9/20 | 0.63 |
| ▸ | CACNA1S | Q13698 | 9/20 | 0.63 |
| ▸ | CACNA1C | Q13936 | 9/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.62 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | THPO | P40225 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955134 | 0.96 | POLB (0.68) | POLBKMT2ACACNA1FCACNA1DCACNA1S | |
| SCHEMBL7132512 | 0.93 | POLB (0.75) | POLBKMT2ACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10364949 | 0.89 | KMT2A (0.65) | POLBKMT2AADORA3CACNA1BMEN1 | |
| SCHEMBL10668372 | 0.85 | POLB (0.55) | POLBKMT2ACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10666490 | 0.84 | CACNA1F (0.57) | POLBKMT2ACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10391380 | 0.84 | CACNA1F (0.63) | POLBKMT2ACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10391383 | 0.84 | CACNA1F (0.63) | POLBKMT2ACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10670264 | 0.83 | KMT2A (0.76) | POLBKMT2ACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10721143 | 0.83 | CACNA1F (0.59) | POLBKMT2ACACNA1FCACNA1DCACNA1S | |
| SCHEMBL10721151 | 0.83 | CACNA1F (0.59) | POLBKMT2ACACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126094-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS. | CERMOL SA (CH) | 1984-11-28 | — | — | EP | claimed |
| WO-1984002132-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS | CERMOL SA (CH) | 1984-06-07 | — | — | WO | claimed |
| EP-0126094-B1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS | CERMOL S.A. (CH) | 1990-06-20 | — | — | EP | disclosed |
| US-4727066-A | CARDIOVASCULAR DISORDERS | CERMOL S.A. (CH) | 1988-02-23 | — | — | US | disclosed |
| US-4656181-A | CARDIOTONIC AGENTS | CERMOL S.A. (CH) | 1987-04-07 | — | — | US | disclosed |
| EP-0126094-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS. | CERMOL SA (CH) | 1984-11-28 | — | — | EP | disclosed |
| WO-1984002132-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS | CERMOL SA (CH) | 1984-06-07 | — | — | WO | disclosed |