Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.65 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.55 |
| ▸ | ITGAL | P20701 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051294 | 1.00 | GHSR (0.65) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL31606451 | 0.97 | GHSR (0.69) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL30051497 | 0.92 | GHSR (0.62) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL31606521 | 0.91 | GHSR (0.68) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL30053040 | 0.91 | GHSR (0.64) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL30223334 | 0.91 | GHSR (0.57) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL31018989 | 0.91 | GHSR (0.58) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL29533411 | 0.90 | GHSR (0.65) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL31606515 | 0.90 | GHSR (0.66) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL30051510 | 0.89 | ACE (0.59) | GHSRITGB2ICAM1ITGALACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217007-A1 | PEPTIDIC CONJUGATES OF SN38 USEFUL IN THE TREATMENT OF CANCER | Fundació Institut de Recerca Biomèdica (IRB Barcelona) (ES) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022064052-A1 | PEPTIDIC CONJUGATES OF SN38 USEFUL IN THE TREATMENT OF CANCER | FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) | 2022-03-31 | — | — | WO | disclosed |