Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.65 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.62 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.62 |
| ▸ | ITGAL | P20701 | 1/20 | 0.62 |
| ▸ | ACE | P12821 | 2/20 | 0.59 |
| ▸ | ECE1 | P42892 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051684 | 0.96 | GHSR (0.63) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL30610088 | 0.96 | GHSR (0.63) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL31609182 | 0.96 | GHSR (0.63) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL30052886 | 0.96 | GHSR (0.63) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL29550930 | 0.96 | GHSR (0.63) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL21641802 | 0.96 | ITGB2 (0.67) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL29533628 | 0.96 | ITGB2 (0.67) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL21641801 | 0.96 | ITGB2 (0.67) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL29144196 | 0.96 | ITGB2 (0.67) | GHSRITGB2ICAM1ITGALACE | |
| SCHEMBL29904257 | 0.96 | ITGB2 (0.67) | GHSRITGB2ICAM1ITGALACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380889-A | Humanized ACE2 polypeptide retarder as well as design and synthesis method and application thereof | 中国科学院大连化学物理研究所 | 2022-04-22 | — | — | CN | claimed |
| US-12622975-B2 | Peptide-conjugated prodrugs | BRANDEIS UNIVERSITY (US) | 2026-05-12 | — | — | US | disclosed |
| CN-114380889-B | Humanized ACE2 polypeptide blocker and design and synthesis method and application thereof | 中国科学院大连化学物理研究所 | 2023-11-17 | — | — | CN | disclosed |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-12-08 | — | — | US | disclosed |
| CN-114380889-A | Humanized ACE2 polypeptide retarder as well as design and synthesis method and application thereof | 中国科学院大连化学物理研究所 | 2022-04-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622975-B2 | Peptide-conjugated prodrugs | PEPD, PAM, VIP | GHSR 429/4885ITGB2 3494/4885ICAM1 2949/4885 |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | VIP, DNPEP, PEPD | GHSR 679/4885ITGB2 3719/4885ICAM1 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.