⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25412878 | 0.76 | HTR2C (0.31) | — | |
| SCHEMBL29497425 | 0.76 | HTR2C (0.31) | — | |
| SCHEMBL29426997 | 0.68 | ABHD6 (0.48) | — | |
| SCHEMBL25412552 | 0.68 | ABHD6 (0.48) | — | |
| SCHEMBL25434991 | 0.67 | ABHD6 (0.44) | — | |
| SCHEMBL26785754 | 0.66 | ABL1 (0.37) | — | |
| SCHEMBL26739269 | 0.63 | MGLL (0.42) | — | |
| SCHEMBL29426759 | 0.63 | MGLL (0.42) | — | |
| SCHEMBL14142880 | 0.63 | GRM7 (0.44) | — | |
| SCHEMBL29497356 | 0.62 | ABHD6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217062-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022063784-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-31 | — | — | WO | disclosed |