Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29427421 | 0.86 | KDM4E (0.44) | KMT2AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29427332 | 0.77 | ELANE (0.33) | ALDH1A1HPGDMAPTFNTAFNTB | |
| SCHEMBL29427322 | 0.76 | GAA (0.41) | KMT2AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29427367 | 0.76 | TP53 (0.59) | KMT2AALDH1A1SMN1; SMN2HSD17B10GAA | |
| SCHEMBL29427366 | 0.76 | KMO (0.49) | KMT2ALMNASMN1; SMN2HSD17B10GAA | |
| SCHEMBL29427418 | 0.74 | GAA (0.34) | KMT2AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL13663041 | 0.72 | LMNA (0.50) | KMT2AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29427372 | 0.71 | LMNA (0.51) | KMT2AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29427334 | 0.71 | HTT (0.48) | KMT2AKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29427305 | 0.70 | CYP1A1 (0.41) | KMT2AKDM4EALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022064453-A1 | NEMATOCIDAL COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2022-03-31 | — | — | WO | claimed |
| WO-2022064453-A1 | NEMATOCIDAL COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2022-03-31 | — | — | WO | disclosed |