Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | GLS | O94925 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13791090 | 0.87 | GAA (0.54) | GAAKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL15623056 | 0.86 | GAA (0.56) | GAAKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL15631894 | 0.83 | ALDH1A1 (0.76) | GAAKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL18953236 | 0.83 | TSHR (0.51) | GAAKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL28941012 | 0.83 | GAA (0.57) | GAAKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL13329858 | 0.83 | KDM4E (0.50) | KMT2AALDH1A1L3MBTL1KDM4EHTT | |
| SCHEMBL29427421 | 0.82 | KDM4E (0.44) | GAAKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL3354341 | 0.81 | HSD17B10 (0.65) | KMT2AALDH1A1KDM4EHTTHPGD | |
| SCHEMBL29427370 | 0.81 | ALDH1A1 (0.44) | GAAKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL1638661 | 0.79 | L3MBTL1 (0.53) | GAAKMT2AMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022064453-A1 | NEMATOCIDAL COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2022-03-31 | — | — | WO | disclosed |