Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP1 | P07148 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 9/20 | 0.38 |
| ▸ | DRD3 | P35462 | 6/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19948204 | 1.00 | FABP1 (0.38) | FABP1DRD2DRD3HTR1DDRD4 | |
| SCHEMBL25323447 | 0.82 | FABP1 (0.39) | FABP1DRD2DRD3HTR1DDRD4 | |
| SCHEMBL6207099 | 0.81 | PPARG (0.43) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL7601041 | 0.80 | DRD2 (0.39) | DRD2DRD3HTR1DDRD4HTR5A | |
| Iodide SCHEMBL7773907 | 0.80 | PPARG (0.42) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL17080387 | 0.79 | FABP1 (0.40) | FABP1DRD2DRD3HTR1DDRD4 | |
| SCHEMBL3082218 | 0.79 | MRGPRX4 (0.46) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL22554976 | 0.78 | FABP1 (0.37) | FABP1DRD2DRD3HTR1DDRD4 | |
| SCHEMBL22208151 | 0.78 | PDE4A (0.37) | FABP1DRD2DRD3HTR1DDRD4 | |
| SCHEMBL30064840 | 0.78 | PDE4A (0.37) | FABP1DRD2DRD3HTR1DDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4216951-A1 | KRAS G12D INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022066646-A1 | KRAS G12D INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-03-31 | — | — | WO | disclosed |