SCHEMBL7601041

SCHEMBL7601041

O=S(=O)(Oc1cccc(C(F)(F)F)c1C(F)(F)F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 9/20 0.39
DRD3 P35462 6/20 0.39
HTR1D P28221 2/20 0.39
DRD4 P21917 4/20 0.36
HTR5A P47898 1/20 0.36
SLC22A12 Q96S37 2/20 0.35
MRGPRX4 Q96LA9 1/20 0.35
DRD1 P21728 2/20 0.34
DRD5 P21918 2/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
PPARG P37231 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7597866 0.90 SLC22A12 (0.33) DRD2DRD3HTR1DSLC22A12MRGPRX4
SCHEMBL6207099 0.84 PPARG (0.43) DRD2DRD3HTR1DDRD4SLC22A12
SCHEMBL15453472 0.83 HSD11B1 (0.36) SLC22A12MRGPRX4
Iodide SCHEMBL7773907 0.82 PPARG (0.42) DRD2DRD3HTR1DDRD4SLC22A12
SCHEMBL19948194 0.81 DRD2 (0.41) DRD2DRD3HTR1DDRD4HTR5A
SCHEMBL3082218 0.81 MRGPRX4 (0.46) DRD2DRD3HTR1DDRD4HTR5A
SCHEMBL15765781 0.81 CNR2 (0.38) SLC22A12MRGPRX4RXRARXRBRXRG
SCHEMBL18374895 0.81 DRD2 (0.35) DRD2DRD3HTR1DDRD4DRD1
SCHEMBL19948204 0.80 FABP1 (0.38) DRD2DRD3HTR1DDRD4HTR5A
SCHEMBL29428702 0.80 FABP1 (0.38) DRD2DRD3HTR1DDRD4HTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020042541-A1 Process for producing bis( trifluoromethyl)benzaldehyde CENTRAL GLASS COMPANY, LIMITED (JP) 2002-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042541-A1 Process for producing bis( trifluoromethyl)benzaldehyde BRPF1, PFAS, FLI1 DRD2 2483/4885DRD3 2723/4885HTR1D 2557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.