Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980211 | 1.00 | MAPT (0.70) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL1105474 | 0.89 | MAPT (0.55) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL29616405 | 0.87 | CYP3A4 (0.83) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL29428987 | 0.85 | MAPT (0.95) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL28272577 | 0.85 | CA12 (0.61) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL29532077 | 0.83 | CYP3A4 (1.00) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL929235 | 0.83 | CYP3A4 (1.00) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL29428994 | 0.80 | MAPT (0.70) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL22118337 | 0.80 | ALDH1A1 (0.70) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL29087860 | 0.80 | ALDH1A1 (0.70) | MAPTALDH1A1KDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057623-B | N-naphthyl indole derivative and synthesis method thereof | 湖南第一师范学院 | 2023-07-21 | — | — | CN | claimed |
| CN-114057623-A | N-naphthyl indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-18 | — | — | CN | claimed |
| CN-115304545-B | Copper-catalyzed selective cyclization of 2-alkynylanilines to quinolines and quinolone derivatives | 湖南大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-114057623-B | N-naphthyl indole derivative and synthesis method thereof | 湖南第一师范学院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115304545-A | Copper-catalyzed selective cyclization of 2-alkynylanilines to quinoline and quinolone derivatives | 湖南大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-114057623-A | N-naphthyl indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-18 | — | — | CN | disclosed |