Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29428992 | 1.00 | MAPT (0.70) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL1105474 | 0.89 | MAPT (0.55) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL29616405 | 0.87 | CYP3A4 (0.83) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL29428987 | 0.85 | MAPT (0.95) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL28272577 | 0.85 | CA12 (0.61) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL29532077 | 0.83 | CYP3A4 (1.00) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL929235 | 0.83 | CYP3A4 (1.00) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL29428994 | 0.80 | MAPT (0.70) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL22118337 | 0.80 | ALDH1A1 (0.70) | MAPTALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL29087860 | 0.80 | ALDH1A1 (0.70) | MAPTALDH1A1KDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912809-B | Non-noble metal-metal organic framework composite material, preparation method and application thereof | 中国科学院福建物质结构研究所 | 2022-03-22 | — | — | CN | claimed |
| CN-109912809-A | Base metal-metal organic framework composite material, preparation method and application | 中国科学院福建物质结构研究所 | 2019-06-21 | — | — | CN | claimed |
| CN-116425717-B | C2-site indoline derivative containing quaternary carbon center as well as preparation method and application thereof | 重庆医科大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-116425717-A | C2-site indoline derivative containing quaternary carbon center as well as green preparation method and application thereof | 重庆医科大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-110642844-B | 3-position indole substituted isobenzofuranone compound and preparation method thereof | 郑州大学 | 2023-03-03 | — | — | CN | disclosed |
| CN-109912809-B | Non-noble metal-metal organic framework composite material, preparation method and application thereof | 中国科学院福建物质结构研究所 | 2022-03-22 | — | — | CN | disclosed |
| CN-109912809-A | Base metal-metal organic framework composite material, preparation method and application | 中国科学院福建物质结构研究所 | 2019-06-21 | — | — | CN | disclosed |
| EP-2295402-B1 | Antibacterial agents | UNIV WASHINGTON (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2295402-A2 | Antibacterial agents | The University of Washington (US) | 2011-03-16 | — | — | EP | disclosed |
| US-20100286144-A1 | HETEROARYL DERIVATIVES | TAKAHASHI YOKO | 2010-11-11 | — | — | US | disclosed |
| US-20100286144-A1 | HETEROARYL DERIVATIVES | TAKAHASHI YOKO | 2010-11-11 | — | — | US | disclosed |
| US-7781479-B2 | Heteroaryl derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-7781479-B2 | Heteroaryl derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20080167306-A1 | Novel Heteroaryl Derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20080167306-A1 | Novel Heteroaryl Derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
| EP-1837329-A1 | NOVEL HETEROARYL DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2007-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286144-A1 | HETEROARYL DERIVATIVES | GPR119, SLC2A1, SLC2A4 | MAPT 4724/4885ALDH1A1 631/4885KDM4E 1146/4885 |
| US-20080167306-A1 | Novel Heteroaryl Derivative | GPR119, SLC2A4, SLC5A2 | MAPT 4727/4885ALDH1A1 699/4885KDM4E 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.