Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696215 | 1.00 | HTR6 (0.43) | HTR6KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL29429049 | 1.00 | HTR6 (0.43) | HTR6KMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL29429027 | 0.92 | HTR6 (0.49) | HTR6KMT2AALDH1A1L3MBTL1HAO1 | |
| SCHEMBL28684397 | 0.92 | HTR6 (0.49) | HTR6KMT2AALDH1A1L3MBTL1HAO1 | |
| SCHEMBL29429090 | 0.92 | HTR6 (0.49) | HTR6KMT2AALDH1A1L3MBTL1HAO1 | |
| SCHEMBL28705207 | 0.87 | HTR6 (0.43) | HTR6KMT2AALDH1A1L3MBTL1HAO1 | |
| SCHEMBL29429103 | 0.87 | HTR6 (0.43) | HTR6KMT2AALDH1A1L3MBTL1HAO1 | |
| SCHEMBL28703811 | 0.87 | HTR6 (0.43) | HTR6KMT2AALDH1A1L3MBTL1HAO1 | |
| SCHEMBL28690173 | 0.87 | KMT2A (0.44) | HTR6KMT2AALDH1A1L3MBTL1HAO1 | |
| SCHEMBL29429023 | 0.87 | KMT2A (0.44) | HTR6KMT2AALDH1A1L3MBTL1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057623-B | N-naphthyl indole derivative and synthesis method thereof | 湖南第一师范学院 | 2023-07-21 | — | — | CN | disclosed |
| CN-114057623-A | N-naphthyl indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-18 | — | — | CN | disclosed |