Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SGK1 | O00141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28686520 | 1.00 | MAPT (0.47) | MAPTSMN1; SMN2HAO1ALDH1A1HPGD | |
| SCHEMBL29429022 | 1.00 | MAPT (0.47) | MAPTSMN1; SMN2HAO1ALDH1A1HPGD | |
| SCHEMBL28684397 | 0.86 | HTR6 (0.49) | MAPTHAO1ALDH1A1HPGDKDM4E | |
| SCHEMBL29429027 | 0.86 | HTR6 (0.49) | MAPTHAO1ALDH1A1HPGDKDM4E | |
| SCHEMBL29429090 | 0.86 | HTR6 (0.49) | MAPTHAO1ALDH1A1HPGDKDM4E | |
| SCHEMBL29429041 | 0.84 | KMT2A (0.44) | HAO1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28690173 | 0.84 | KMT2A (0.44) | HAO1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL29429045 | 0.84 | KMT2A (0.44) | HAO1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28690221 | 0.84 | KMT2A (0.44) | HAO1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL29429036 | 0.84 | KMT2A (0.44) | HAO1ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057623-A | N-naphthyl indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-18 | — | — | CN | disclosed |