Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28932895 | 1.00 | KMT2A (0.41) | KMT2AL3MBTL1HTR6HAO1NTRK1 | |
| SCHEMBL29429052 | 0.90 | HTR6 (0.43) | KMT2AL3MBTL1HTR6HAO1APP | |
| SCHEMBL29429059 | 0.90 | HTR6 (0.43) | KMT2AL3MBTL1HTR6HAO1APP | |
| SCHEMBL29429025 | 0.90 | HTR6 (0.43) | KMT2AL3MBTL1HTR6HAO1APP | |
| SCHEMBL28683381 | 0.90 | HTR6 (0.43) | KMT2AL3MBTL1HTR6HAO1APP | |
| SCHEMBL28705207 | 0.90 | HTR6 (0.43) | KMT2AL3MBTL1HTR6HAO1APP | |
| SCHEMBL29429103 | 0.90 | HTR6 (0.43) | KMT2AL3MBTL1HTR6HAO1APP | |
| SCHEMBL28696214 | 0.87 | HTR6 (0.43) | KMT2AL3MBTL1HTR6HAO1NTRK1 | |
| SCHEMBL28684397 | 0.86 | HTR6 (0.49) | KMT2AL3MBTL1HTR6HAO1NTRK1 | |
| SCHEMBL29429090 | 0.86 | HTR6 (0.49) | KMT2AL3MBTL1HTR6HAO1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057623-B | N-naphthyl indole derivative and synthesis method thereof | 湖南第一师范学院 | 2023-07-21 | — | — | CN | disclosed |
| CN-114057623-A | N-naphthyl indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-18 | — | — | CN | disclosed |